UniProt Accession

 D3Z7R4_MOUSE; D3Z7R4 

Genbank Protein ID

 AC117199; AC122472; AC124436; AC141899; AC162908; AC163645 

Genbank Nucleotide ID

  

Protein Name

 Synaptotagmin-1 

Protein Synonyms/Alias

  

Gene Name

 Syt1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
104	GKNAINMKDVKDLGK	ubiquitination	[1]
114	KDLGKTMKDQDDDAE	ubiquitination	[1]
186	KVFLLPDKKKKFETK	ubiquitination	[1]
197	FETKVHRKTLNPVFN	ubiquitination	[1]
210	FNEQFTFKVPYSELG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 236 AA 

Protein Sequence

Gene Ontology

 GO:0043005; C:neuron projection; IDA:MGI.
 GO:0042734; C:presynaptic membrane; IDA:MGI.
 GO:0030141; C:secretory granule; IDA:MGI.
 GO:0030672; C:synaptic vesicle membrane; IDA:MGI.
 GO:0005509; F:calcium ion binding; IDA:MGI.
 GO:0005544; F:calcium-dependent phospholipid binding; TAS:MGI.
 GO:0050750; F:low-density lipoprotein particle receptor binding; ISO:MGI.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0016079; P:synaptic vesicle exocytosis; IMP:MGI. 

Interpro

 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR020477; C2_dom.
 IPR018029; C2_membr_targeting.
 IPR001565; Synaptotagmin.
 IPR015428; Synaptotagmin1. 

Pfam

 PF00168; C2 

SMART

 SM00239; C2 

PROSITE

 PS50004; C2 

PRINTS

 PR00360; C2DOMAIN.
 PR00399; SYNAPTOTAGMN.