UniProt Accession

 A2A6G6_MOUSE; A2A6G6 

Genbank Protein ID

 AL596446 

Genbank Nucleotide ID

  

Protein Name

 LIM and SH3 domain protein 1 

Protein Synonyms/Alias

  

Gene Name

 Lasp1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
60	EFEKNKGKGFSVVAD	acetylation	[1]
60	EFEKNKGKGFSVVAD	ubiquitination	[2]
76	PELQRIKKTQDQISN	acetylation	[1, 3]
76	PELQRIKKTQDQISN	succinylation	[3]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 89 AA 

Protein Sequence

Gene Ontology

 GO:0030864; C:cortical actin cytoskeleton; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005925; C:focal adhesion; IDA:MGI.
 GO:0051015; F:actin filament binding; IDA:MGI.
 GO:0015075; F:ion transmembrane transporter activity; IEA:Compara.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR000900; Nebulin_35r-motif.
 IPR001781; Znf_LIM. 

Pfam

 PF00880; Nebulin 

SMART

  

PROSITE

 PS51216; NEBULIN 

PRINTS