CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033800
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytokine-like nuclear factor n-pac, isoform CRA_a 
Protein Synonyms/Alias
  
Gene Name
 N-PAC 
Gene Synonyms/Alias
 hCG_15180 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
511NILQGNFKPDFYLKYubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 569 AA 
Protein Sequence
MGGAGATCCS RRPVRRRWLG GKMAAVSLRL GDLVWGKLGR YPPWPGKIVN PPKDLKKPRG 60
KKCFFVKFFG TEDHAWIKVE QLKPYHAHKE EMIKINKGKR FQQAVDAVEE FLRRAKGKDQ 120
TSSHNSSDDK NRRNSSEERS RPNSGDEKRK LSLSEGKVKK NMGEGKKRVS SGSSERGSKS 180
PLKRAQEQSP RKRGRPPKDE KDLTIPESST VKGMMAGPMA AFKWQPTASE PVKDADPHFH 240
HFLLSQTEKP AVCYQAITKK LKICEEETGS TSIQAADSTA VNGSITPTDK KIGFLGLGLM 300
GSGIVSNLLK MGHTVTVWNR TAEKEGARLG RTPAEVVSTC DITFACVSDP KAAKDLVLGP 360
SGVLQGIRPG KCYVDMSTVD ADTVTELAQV IVSRGGRFLE APVSGNQQLS NDGMLVILAA 420
GDRGLYEDCS SCFQAMGKTS FFLGEVGNAA KMMLIVNMVQ GSFMATIAEG LTLAQVTGQS 480
QQTLLDILNQ GQLASIFLDQ KCQNILQGNF KPDFYLKYIQ KDLRLAIALG DAVNHPTPMA 540
AAANEVYKRA KALDQSDNDM SAVYRAYIH 569 
Gene Ontology
 GO:0050662; F:coenzyme binding; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
 GO:0006098; P:pentose-phosphate shunt; IEA:InterPro. 
Interpro
 IPR008927; 6-PGluconate_DH_C-like.
 IPR006115; 6PGDH_NADP-bd.
 IPR017956; AT_hook_DNA-bd_motif.
 IPR013328; DH_multihelical.
 IPR015815; HIBADH-type.
 IPR016040; NAD(P)-bd_dom.
 IPR000313; PWWP. 
Pfam
 PF03446; NAD_binding_2
 PF00855; PWWP 
SMART
 SM00384; AT_hook 
PROSITE
 PS50812; PWWP 
PRINTS