CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-045571
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cytosol aminopeptidase 
Protein Synonyms/Alias
  
Gene Name
 Lap3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
11LVLGIYSKDKDDDVPacetylation[1]
13LGIYSKDKDDDVPQFacetylation[1]
29SAGENFNKLVSGRLRacetylation[1]
47NISGPPLKAGKTRTFacetylation[1]
86QENWHEGKENIRAAVacetylation[1]
189RFAEVIEKNLKSASSacetylation[1]
423ADVNNLGKYRSAGACacetylation[1]
457IAGVMTNKDEIPYLRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 487 AA 
Protein Sequence
TQGLVLGIYS KDKDDDVPQF TSAGENFNKL VSGRLREMLN ISGPPLKAGK TRTFYGLHQD 60
FPSVVVVGLG KRSAGVDDQE NWHEGKENIR AAVAAGCRQV QDLELPSVEV DPCGDAQAAA 120
EGAVLGLYEY DDLKQKKKVA VSAKLHGSGD LEAWEKGVLF ASGQNLARQL MESPANEMTP 180
TRFAEVIEKN LKSASSKTEV HIRTKSWIEE QEMGSFLSVA KGSEEPPVFL EIHYTGSPNA 240
TEAPLVFVGK GITFDSGGIS IKASANMDLM RADMGGAATI CSAIVSAAKL NLPINIIGLA 300
PLCENMPSGK ANKPGDVVRA RNGKTIQVDN TDAEGRLILA DALCYAHTFN PKVIINAATL 360
TGAMDVALGS GATGVFTNSS WLWNKLFEAS VETGDRVWRM PLFEHYTRQV IDCQLADVNN 420
LGKYRSAGAC TAAAFLREFV THTKWAHLDI AGVMTNKDEI PYLRKGMSGR PTRTLIEFLL 480
RFSKDSS 487 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0004177; F:aminopeptidase activity; IEA:InterPro.
 GO:0030145; F:manganese ion binding; IEA:InterPro.
 GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:InterPro. 
Interpro
 IPR011356; Leucine_aapep/pepB.
 IPR000819; Peptidase_M17_C.
 IPR023042; Peptidase_M17_leu_NH2_pept.
 IPR008283; Peptidase_M17_N. 
Pfam
 PF00883; Peptidase_M17
 PF02789; Peptidase_M17_N 
SMART
  
PROSITE
 PS00631; CYTOSOL_AP 
PRINTS
 PR00481; LAMNOPPTDASE.