CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041738
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoribosylglycinamide formyltransferase, isoform CRA_a 
Protein Synonyms/Alias
 Protein Gart 
Gene Name
 Gart 
Gene Synonyms/Alias
 rCG_58778 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
249VPKDLLVKIKNTILQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1010 AA 
Protein Sequence
MAARVLVIGS GGREHTLAWK LAQSPHVKQV LVAPGNAGTA SAGKISNAAV SINDHTALAR 60
FCKDEKIELV VVGPEAPLAA GIVGDLTSAG VRCFGPTAQA ALLESSKKFA KEFMDRHGVP 120
TAQWRAFTSP EDACSFIMSA DFPALVVKAS GLAAGKGVIV AKSKAEACEA VQEIMQEKSF 180
GAAGETVVVE ELLEGEEVSC LCFTDGKTVA PMPPAQDHKR LLDGDRGPNT GGMGAYCPAP 240
QVPKDLLVKI KNTILQRTVD GMQQEGVPYT GILYAGIMLT KDGPKVLEFN CRFGDPECQV 300
ILPLLKSDLY EVIQSTFDGL LSESPPVWLE NHSAVTVVMA SGGYPGAYTK GVEITGFPEA 360
QALGLQVFHA GTALKDAKVV TSGGRVLTVT AVRENLMSAL DEARKGLAAL KFEGAVYRKD 420
IGFRAVAFLQ RPRGLTYKDS GVDIAAGNML VKKIQPLAKA TSRPGCSVDL GGFAGLFDLK 480
AAGFKDPLLA SGTDGVGTKL KIAQLCNKHD SIGQDLVAMC VNDILAQGAE PLFFLDYFSC 540
GKLDLSTTEA VVAGIAAACR QAGCALLGGE TAEMPDMYPP GEYDLAGFAV GAMERHQKLP 600
QLERIAEGDA VIGVASSGLH SNGFSLVRKI VERSSLQYSS PAPGGCGDQT LGDLLLTPTR 660
IYSHSLLPII RSGRVKAFAH ITGGGLLENI PRVLPRKLGV DLDAYTWRVP KVFSWLQQEG 720
QLSEEEMART FNCGVGAALV VSKDQTEQIL HDIRQHQEDA WVIGSVVECP EDSPRVRVKN 780
LIETMQTKGS VVTNGFLRSN FPSQQKKARV AVLISGTGSN LQALIDSTRD PKSSSHIVLV 840
ISNKAAVAGL DRAERAGIPT RVINHKLYKS RVEFDNAVDH VLEEFSVDIV CLAGFMRILS 900
GPFVRKWDGK MLNIHPSLLP SFKGSNAHEQ VLEAGVTITG CTVHFVAEDV DAGQIILQEA 960
VPVQRDDTVA TLSERVKAAE HKIFPAALQL VASGAVQLGE DGKIHWAREQ 1010 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0008168; F:methyltransferase activity; IEA:InterPro.
 GO:0004637; F:phosphoribosylamine-glycine ligase activity; IDA:RGD.
 GO:0004641; F:phosphoribosylformylglycinamidine cyclo-ligase activity; IDA:RGD.
 GO:0004644; F:phosphoribosylglycinamide formyltransferase activity; IDA:RGD.
 GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
 GO:0003360; P:brainstem development; IEP:RGD.
 GO:0021549; P:cerebellum development; IEP:RGD.
 GO:0021987; P:cerebral cortex development; IEP:RGD.
 GO:0009235; P:cobalamin metabolic process; TAS:RGD.
 GO:0006544; P:glycine metabolic process; IDA:RGD.
 GO:0032259; P:methylation; IEA:GOC.
 GO:0009113; P:purine nucleobase biosynthetic process; IEA:InterPro.
 GO:0010035; P:response to inorganic substance; IDA:RGD.
 GO:0010033; P:response to organic substance; IDA:RGD.
 GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IDA:RGD.
 GO:0046654; P:tetrahydrofolate biosynthetic process; IDA:RGD. 
Interpro
 IPR010918; AIR_synth_C_dom.
 IPR000728; AIR_synth_N_dom.
 IPR011761; ATP-grasp.
 IPR013815; ATP_grasp_subdomain_1.
 IPR013816; ATP_grasp_subdomain_2.
 IPR002376; Formyl_transf_N.
 IPR001555; GART_AS.
 IPR016185; PreATP-grasp_dom.
 IPR020561; PRibGlycinamid_synth_ATP-grasp.
 IPR000115; PRibGlycinamide_synth.
 IPR020560; PRibGlycinamide_synth_C-dom.
 IPR020559; PRibGlycinamide_synth_CS.
 IPR020562; PRibGlycinamide_synth_N.
 IPR004733; PurM_cligase.
 IPR016188; PurM_N-like.
 IPR004607; PurN_trans.
 IPR011054; Rudment_hybrid_motif. 
Pfam
 PF00586; AIRS
 PF02769; AIRS_C
 PF00551; Formyl_trans_N
 PF01071; GARS_A
 PF02843; GARS_C
 PF02844; GARS_N 
SMART
  
PROSITE
 PS50975; ATP_GRASP
 PS00184; GARS
 PS00373; GART 
PRINTS