CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043672
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Solute carrier family 15 member 4 
Protein Synonyms/Alias
  
Gene Name
 SLC15A4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
218TYSCCSQKRSGERQSubiquitination[1, 2, 3, 4]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 238 AA 
Protein Sequence
XSNLVLFLNG APFCWEGAQA SEALLLFMGL TYLGSPFGGW LADARLGRAR AILLSLALYL 60
LGMLAFPLLA APATRAALCG SARLLNCTAP GPDAAARCCS PATFAGLVLV GLGVATVKAN 120
ITPFGADQVK DRGPEATRRF FNWFYWSINL GAILSLGGIA YIQQNVSFVT GYAIPTVCVG 180
LAFVVFLCGQ SVFITKPPDG SAFTDMFKIL TYSCCSQKRS GERQSNGCRQ HMFYRVFI 238 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005215; F:transporter activity; IEA:InterPro.
 GO:0006857; P:oligopeptide transport; IEA:InterPro. 
Interpro
 IPR016196; MFS_dom_general_subst_transpt.
 IPR000109; POT_fam.
 IPR018456; PTR2_symporter_CS. 
Pfam
 PF00854; PTR2 
SMART
  
PROSITE
 PS01023; PTR2_2 
PRINTS