CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023155
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 777 
Protein Synonyms/Alias
  
Gene Name
 ZNF777 
Gene Synonyms/Alias
 KIAA1285 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
263ENMENLLKNRNFWILubiquitination[1]
791CGKRFTQKHHLLEHQubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 285 356 KRAB.
 ZN_FING 546 568 C2H2-type 1.
 ZN_FING 574 596 C2H2-type 2.
 ZN_FING 636 658 C2H2-type 3.
 ZN_FING 664 686 C2H2-type 4.
 ZN_FING 694 716 C2H2-type 5.
 ZN_FING 722 744 C2H2-type 6.
 MOD_RES 496 496 Phosphoserine.
 MOD_RES 502 502 Phosphoserine.  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 760 AA 
Protein Sequence
MENQRSSPLS FPSVPQEETL RQAPAGLPRE TLFQSRVLPP KEIPSLSPTI PRQGSLPQTS 60
SAPKQETSGR MPHVLQKGPS LLCSAASEQE TSLQGPLASQ EGTQYPPPAA AEQEVSLLSH 120
SPHHQEAPVH SPEAPEKDPL TLSPTVPETD MDPLLQSPVS QKDTPFQISS AVQKEQPLPT 180
AEITRLAVWA AVQAVERKLE AQAMRLLTLE GRTGTNEKKI ADCEKTAVEF ANHLESKWVV 240
LGTLLQEYGL LQRRLENMEN LLKNRNFWIL RLPPGSNGEV PKVPVTFDDV AVHFSEQEWG 300
NLSEWQKELY KNVMRGNYES LVSMDYAISK PDLMSQMERG ERPTMQEQED SEEGETPTDP 360
SAAHDGIVIK IEVQTNDEGS ESLETPEPLM GQVEEHGFQD SELGDPCGEQ PDLDMQEPEN 420
TLEESTEGSS EFSELKQMLV QQRNCTAEGI VIKTEEQDEE EEEEEEDELP QHLQSLGQLS 480
GRYEASMYQT PLPGEMSPEG EESPPPLQLG NPAVKRLAPS VHGERHLSEN RGASSQQQRN 540
RRGERPFTCM ECGKSFRLKI NLIIHQRNHI KEGPYECAEC EISFRHKQQL TLHQRIHRVR 600
GGCVSPERGP TFNPKHALKP RPKSPSSGSG GGGPKPYKCP ECDSSFSHKS SLTKHQITHT 660
GERPYTCPEC KKSFRLHISL VIHQRVHAGK HEVSFICSLC GKSFSRPSHL LRHQRTHTGE 720
RPFKCPECEK SFSEKSKLTN HCRVHSRERP HACPECGKSF IRKHHLLEHR RIHTGERPYH 780
CAECGKRFTQ KHHLLEHQRA HTGERPYPCT HCAKCFRYKQ SLKYHLRTHT GE 832 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR022137; DUF3669_Znf.
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF12417; DUF3669
 PF01352; KRAB
 PF00096; zf-C2H2 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS