UniProt Accession

 LEG9_MOUSE; O08573; O08572; Q3UKE5 

Genbank Protein ID

 U55061; U55060; AK146044; AL592551; AL592185; AL592185; AL592551; CH466556 

Genbank Nucleotide ID

 AAB51190.1; AAB51189.1; BAE26856.1; CAI24050.1; CAI24050.1; CAI25276.1; CAI25276.1; EDL15600.1 

Protein Name

 Galectin-9 

Protein Synonyms/Alias

 Gal-9 

Gene Name

 Lgals9 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
110	LVQRSEFKVMVNKKF	acetylation	[1]

Reference

 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Binds galactosides. May play a role in thymocyte- epithelial interactions relevant to the biology of the thymus. Is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death (By similarity). 

Sequence Annotation

 DOMAIN 17 147 Galectin 1.
 DOMAIN 225 353 Galectin 2.
 REGION 81 87 Beta-galactoside binding 1.
 REGION 285 291 Beta-galactoside binding 2 (By
 BINDING 47 47 Beta-galactoside 1.
 BINDING 60 60 Beta-galactoside 1.
 BINDING 64 64 Beta-galactoside 1.
 BINDING 74 74 Beta-galactoside 1.
 BINDING 265 265 Beta-galactoside 2 (By similarity).
 BINDING 269 269 Beta-galactoside 2 (By similarity).
 BINDING 279 279 Beta-galactoside 2 (By similarity).  

Keyword

 3D-structure; Alternative splicing; Complete proteome; Cytoplasm; Lectin; Reference proteome; Repeat; Secreted. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 353 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
 GO:0030246; F:carbohydrate binding; ISS:UniProtKB.
 GO:0016936; F:galactoside binding; ISA:MGI.
 GO:0007157; P:heterophilic cell-cell adhesion; ISA:MGI. 

Interpro

 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR001079; Galectin_CRD. 

Pfam

 PF00337; Gal-bind_lectin 

SMART

 SM00908; Gal-bind_lectin
 SM00276; GLECT 

PROSITE

 PS51304; GALECTIN 

PRINTS