| Tag | Content |
|---|
| CPLM ID | CPLM-016458 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proton-coupled amino acid transporter 2 |
Protein Synonyms/Alias | Proton/amino acid transporter 2; Solute carrier family 36 member 2; Tramdorin-1 |
Gene Name | Slc36a2 |
Gene Synonyms/Alias | Pat2; Tramd1 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 25 | LDLPESAKKLQSQDP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine. |
Sequence Annotation | |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Cytoplasm; Membrane; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 478 AA |
Protein Sequence | MSVTKSARSP QVATPLNLDL PESAKKLQSQ DPSPANGSSS ESSKKTKGIT GFQTLVHLVK 60
GNMGTGILGL PLAVKNAGIL MGPLSLLVMG LIACHCMHIL VRCAQRFCHR LNKPFMDYGD 120
TVMHGLAFSP NAWLQNHAHW GRRVVSFFLI VTQLGFCCVY IVFLADNLKQ VVEAVNSTTI 180
SCHKNETVVL TPTMDSRLYM LSFLPVLGLL VFVRNLRVLT IFSLLANISM LVSLVIIAQY 240
IIQEIPDASQ LPLVASWKTY PLFFGTAIFS FESIGVVLPL ENKMKDARGF PTILSLGMSI 300
ITTLYIAIGA LGYLRFGDDI KASITLNLPN CWLYQSVKLL YVVGILCTYA LQFYVPAEII 360
IPLAVSQVSK RWALPVDLSI RLALVCLTCM LAILIPRLDL VLSLVGSVSS SALALIIPPL 420
LEVVTYYGEG ISPLTVTKDA LISILGFMGF VVGTYQALDE LIKSGNSPAL SNSTMFIQ 478 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IDA:MGI. GO:0015187; F:glycine transmembrane transporter activity; IDA:MGI. GO:0005280; F:hydrogen:amino acid symporter activity; IDA:MGI. GO:0015180; F:L-alanine transmembrane transporter activity; IDA:MGI. GO:0015193; F:L-proline transmembrane transporter activity; IDA:MGI. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |