| Tag | Content |
|---|
| CPLM ID | CPLM-011531 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative Xaa-Pro aminopeptidase FRA1 |
Protein Synonyms/Alias | Fe repressor of activation 1 |
Gene Name | FRA1 |
Gene Synonyms/Alias | YLL029W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 685 | LIKKATEKGNFLKFE | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in the regulation of the iron regulon in responss to decreased mitochondrial iron-sulfur cluster synthesis. |
Sequence Annotation | METAL 551 551 Manganese 2 (Potential).
METAL 562 562 Manganese 1 (Potential).
METAL 562 562 Manganese 2 (Potential).
METAL 660 660 Manganese 1 (Potential).
METAL 674 674 Manganese 1 (Potential).
METAL 674 674 Manganese 2 (Potential).
MOD_RES 69 69 Phosphoserine.
MOD_RES 92 92 Phosphoserine.
MOD_RES 95 95 Phosphoserine. |
Keyword | Aminopeptidase; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Manganese; Metal-binding; Metalloprotease; Phosphoprotein; Protease; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 749 AA |
Protein Sequence | MTSKPSTSDG RAHSISHVPG THMRGTSASH SPRPFRPCAD CTCSPGLLSR QGRRASLFLR 60
QLENSRRSSS MLLNELKGAG GGSSAGNGSV YSCDSLCAVN REVNTTDRLL KLRQEMKKHD 120
LCCYIVPSCD EHQSEYVSLR DQRRAFISGF SGSAGVACIT RDLLNFNDDH PDGKSILSTD 180
GRYFNQARQE LDYNWTLLRQ NEDPITWQEW CVREALEMAK GLGNKEGMVL KIGIDPKLIT 240
FNDYVSFRKM IDTKYDAKGK VELVPVEENL VDSIWPDFET LPERPCNDLL LLKYEFHGEE 300
FKDKKEKLLK KLNDKASSAT TGRNTFIVVA LDEICWLLNL RGSDIDYNPV FFSYVAINED 360
ETILFTNNPF NDDISEYFKI NGIEVRPYEQ IWEHLTKITS QASSAEHEFL IPDSASWQMV 420
RCLNTSTNAN GAIAKKMTAQ NFAIIHSPID VLKSIKNDIE IKNAHKAQVK DAVCLVQYFA 480
WLEQQLVGRE ALIDEYRAAE KLTEIRKTQR NFMGNSFETI SSTGSNAAII HYSPPVENSS 540
MIDPTKIYLC DSGSQFLEGT TDITRTIHLT KPTKEEMDNY TLVLKGGLAL ERLIFPENTP 600
GFNIDAIARQ FLWSRGLDYK HGTGHGIGSF LNVHEGPMGV GFRPHLMNFP LRAGNIISNE 660
PGYYKDGEYG IRIESDMLIK KATEKGNFLK FENMTVVPYC RKLINTKLLN EEEKTQINEY 720
HARVWRTIVH FLQPQSISYK WLKRETSPL 749 |
Gene Ontology | GO:0005829; C:cytosol; IDA:SGD. GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW. GO:0034396; P:negative regulation of transcription from RNA polymerase II promoter in response to iron; IMP:SGD. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |