CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033558
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Propionyl-CoA carboxylase beta chain, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 PCCB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
232ITGPDVVKSVTNEDVubiquitination[1]
248QEELGGAKTHTTMSGubiquitination[1, 2]
453KVTVITRKAYGGAYDubiquitination[2]
465AYDVMSSKHLCGDTNubiquitination[2]
509AQAEYIEKFANPFPAubiquitination[2]
546LDVLASKKVQRPWRKubiquitination[2]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 559 AA 
Protein Sequence
MAAALRVAAV GARLSVLASG LRAAVRSLCS QATSVNERIE NKRRTALLGG GQRRIDAQHK 60
RGKLTARERI SLLLDPGSFV ESDMFVEHRC ADFGMAADKN KFPGDSVVTG RGRINGRLVY 120
VFSQDFTVFG GSLSGAHAQK ICKIMDQAIT VGAPVIGLND SGGARIQEGV ESLAGYADIF 180
LRNVTASGVI PQISLIMGPC AGGAVYSPAL TDFTFMVKDT SYLFITGPDV VKSVTNEDVT 240
QEELGGAKTH TTMSGVAHRA FENDVDALCN LRDFFNYLPL SSQDPAPVRE CHDPSDRLVP 300
ELDTIVPLES TKAYNMVDII HSVVDEREFF EIMPNYAKNI IVGFARMNGR TVGIVGNQPK 360
VASDSISFTP WNYARRQYRP YFAGCLDINS SVKGARFVRF CDAFNIPLIT FVDVPGFLPG 420
TAQEYGGIIR HGAKLLYAFA EATVPKVTVI TRKAYGGAYD VMSSKHLCGD TNYAWPTAEI 480
AVMGAKGAVE IIFKGHENVE AAQAEYIEKF ANPFPAAVRG FVDDIIQPSS TRARICCDLD 540
VLASKKVQRP WRKHANIPL 559 
Gene Ontology
 GO:0016874; F:ligase activity; IEA:InterPro. 
Interpro
 IPR000022; Carboxyl_trans.
 IPR011763; COA_CT_C.
 IPR011762; COA_CT_N. 
Pfam
 PF01039; Carboxyl_trans 
SMART
  
PROSITE
 PS50989; COA_CT_CTER
 PS50980; COA_CT_NTER 
PRINTS