CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002544
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Iron(3+)-hydroxamate import ATP-binding protein FhuC 
Protein Synonyms/Alias
 Ferric hydroxamate uptake protein C; Ferrichrome transport ATP-binding protein FhuC; Iron(III)-hydroxamate import ATP-binding protein FhuC 
Gene Name
 fhuC 
Gene Synonyms/Alias
 b0151; JW0147 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
38SLTFPAGKVTGLIGHacetylation[1]
138AISLVGLKPLAHRLVacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
 Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Responsible for energy coupling to the transport system. 
Sequence Annotation
 DOMAIN 12 248 ABC transporter.
 NP_BIND 44 51 ATP (Potential).
 NP_BIND 168 179 ATP (Potential).  
Keyword
 ATP-binding; Cell inner membrane; Cell membrane; Complete proteome; Hydrolase; Ion transport; Iron; Iron transport; Membrane; Nucleotide-binding; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 265 AA 
Protein Sequence
MQEYTNHSDT TFALRNISFR VPGRTLLHPL SLTFPAGKVT GLIGHNGSGK STLLKMLGRH 60
QPPSEGEILL DAQPLESWSS KAFARKVAYL PQQLPPAEGM TVRELVAIGR YPWHGALGRF 120
GAADREKVEE AISLVGLKPL AHRLVDSLSG GERQRAWIAM LVAQDSRCLL LDEPTSALDI 180
AHQVDVLSLV HRLSQERGLT VIAVLHDINM AARYCDYLVA LRGGEMIAQG TPAEIMRGET 240
LEMIYGIPMG ILPHPAGAAP VSFVY 265 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0015623; F:iron-chelate-transporting ATPase activity; IEA:EC.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS