CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017606
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein FAM98A 
Protein Synonyms/Alias
  
Gene Name
 FAM98A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
297KTACAINKVLMGRVPubiquitination[1]
325PEMPPWQKRQDGPQQubiquitination[2, 3, 4, 5]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling.
 Xu G, Paige JS, Jaffrey SR.
 Nat Biotechnol. 2010 Aug;28(8):868-73. [PMID: 20639865]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [5] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 519 AA 
Protein Sequence
MECDLMETDI LESLEDLGYK GPLLEDGALS QAVSAGASSP EFTKLCAWLV SELRVLCKLE 60
ENVQATNSPS EAEEFQLEVS GLLGEMNCPY LSLTSGDVTK RLLIQKNCLL LLTYLISELE 120
AARMLCVNAP PKKAQEGGGS EVFQELKGIC IALGMSKPPA NITMFQFFSG IEKKKLKETL 180
AKVPPNHVGK PLLKKPMGPA HWEKIEAINQ AIANEYEVRR KLLIKRLDVT VQSFGWSDRA 240
KSQTEKLAKV YQPKRSVLSP KTTISVAHLL AARQDLSKIL RTSSGSIREK TACAINKVLM 300
GRVPDRGGRP NEIEPPPPEM PPWQKRQDGP QQQTGGRGGG RGGYEHSSYG GRGGHEQGGG 360
RGGRGGYDHG GRGGGRGNKH QGGWTDGGSG GGGGYQDGGY RDSGFQPGGY HGGHSSGGYQ 420
GGGYGGFQTS SSYTGSGYQG GGYQQDNRYQ DGGHHGDRGG GRGGRGGRGG RGGRAGQGGG 480
WGGRGSQNYH QGGQFEQHFQ HGGYQYNHSG FGQGRHYTS 519 
Gene Ontology
  
Interpro
 IPR018797; Uncharacterised_FAM98. 
Pfam
 PF10239; DUF2465 
SMART
  
PROSITE
  
PRINTS