CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042443
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Thyroid peroxidase 
Protein Synonyms/Alias
  
Gene Name
 TPO 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
764RWTRTGTKSTLPISEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 864 AA 
Protein Sequence
QLLSFSKLPE PTSGVIARAA EIMETSIQAM KRKVNLKTQQ SQHPTDALSE DLLSIIANMS 60
GCLPYMLPPK CPNTCLANKY RPITGACNNR DHPRWGASNT ALARWLPPVY EDGFSQPRGW 120
NPGFLYNGFP LPPVREVTRH VIQVSNEVVT DDDRYSDLLM AWGQYIDHDI AFTPQSTSKA 180
AFGGGADCQM TCENQNPCFP IQLPEEARPA AGTACLPFYR SSAACGTGDQ GALFGNLSTA 240
NPRQQMNGLT SFLDASTVYG SSPALERQLR NWTSAEGLLR VHARLRDSGR AYLPFVPPRA 300
PAACAPEPGI PGETRGPCFL AGDGRASEVP SLTALHTLWL REHNRLAAAL KALNAHWSAD 360
AVYQEARKVV GALHQIITLR DYIPRILGPE AFQQYVGPYE GYDSTANPTV SNVFSTAAFR 420
FGHATIHPLV RRLDASFQEH PDLPGLWLHQ AFFSPWTLLR GGGLDPLIRG LLARPAKLQV 480
QDQLMNEELT ERLFVLSNSS TLDLASINLQ RGRDHGLPGY NEWREFCGLP RLETPADLST 540
AIASRSVADK ILDLYKHPDN IDVWLGGLAE NFLPRARTGP LFACLIGKQM KALRDGDWFW 600
WENSHVFTDA QRRELEKHSL SRVICDNTGL TRVPMDAFQV GKFPEDFESC DSITGMNLEA 660
WRETFPQDDK CGFPESVENG DFVHCEESGR RVLVYSCRHG YELQGREQLT CTQEGWDFQP 720
PLCKDSGRLP RVTWISMSLA ALLIGGFAGL TSTVICRWTR TGTKSTLPIS ETGGGTPELR 780
CGKHQAVGTS PQRAAAQDSE QVGHTMPHVS SCHRSGWTGS GCRSSSAGAP CIFLFTPCFL 840
VRSAPSSGRF YLQANDSEPE CEPA 864 
Gene Ontology
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0004601; F:peroxidase activity; IEA:InterPro.
 GO:0006979; P:response to oxidative stress; IEA:InterPro. 
Interpro
 IPR010255; Haem_peroxidase.
 IPR002007; Haem_peroxidase_animal.
 IPR019791; Haem_peroxidase_animal_subgr.
 IPR000436; Sushi_SCR_CCP. 
Pfam
 PF03098; An_peroxidase
 PF00084; Sushi 
SMART
 SM00032; CCP 
PROSITE
 PS50292; PEROXIDASE_3
 PS50923; SUSHI 
PRINTS
 PR00457; ANPEROXIDASE.