CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037661
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase 
Protein Synonyms/Alias
  
Gene Name
 ALG8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
172SYCFTANKPDGSIRWubiquitination[1, 2]
180PDGSIRWKSFSFVRVubiquitination[3]
222FSRLFPFKRGLCHAYubiquitination[4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 242 AA 
Protein Sequence
MPSHPHIATS EWTLDYPPFF AWFEYILSHV AKYFDQEMLN VHNLNYSSSR TLLFQRFSVI 60
FMDVLFVYAV RECCKCIDGK KVGKELTEKP KFILSVLLLW NFGLLIVDHI HFQYNGFLFG 120
LMLLSIARLF QKRHMEGAFL FAVLLHFKHI YLYVAPAYGV YLLRSYCFTA NKPDGSIRWK 180
SFSFVRVISL GLVVFLVSAL SLGPFLALNQ LPQVFSRLFP FKRGLCHAYW APNFWALYNA 240
LD 242 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.
 GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro. 
Interpro
 IPR004856; Glyco_trans_ALG6/ALG8. 
Pfam
 PF03155; Alg6_Alg8 
SMART
  
PROSITE
  
PRINTS