| Tag | Content |
|---|
| CPLM ID | CPLM-023431 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Eukaryotic translation initiation factor 3 subunit L |
Protein Synonyms/Alias | eIF3l |
Gene Name | CG5642 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 526 | FFVRKILKFNDLNRK | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (By similarity). |
Sequence Annotation | |
Keyword | Complete proteome; Cytoplasm; Initiation factor; Protein biosynthesis; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 539 AA |
Protein Sequence | MYGGDEYATN SDYYDDYAHT GDPQLDMEYE RNYYAARMPD NVKYFLINFC QAIKEGNLYD 60
IQNMYENTFP QISDHHFDKT AWPEEQEVAA IVDNDKVFLI LYKELYYRHI HARIPGGPKL 120
EQRINSFFNY CDFFNLIISA QNPVMLELPD IWLWELVDEF VYQFQNFAQY RARLTEKSQD 180
EIQQLCVNHS NEWSILCILN VLHSLVDISN IKKQLEAISQ GVDPQTVAGD FGKLSFYKML 240
GYFSLVGLLR VHSLLGDYYQ AIKVLEPIEI HKKSAYSHIP ACQISTSYYV GFAYMMMRRY 300
ADAIRTFSDI LLYIQRTKQL YSTRSYQNDQ INKQAEQMYH LLAICLVLHP QCIDESIQQV 360
LREKNYHDAM FKMQCGDLEV FKSFFVFACP RFVSPCPPAV DAPMDDYVKD PMEHQLQVFM 420
DEVRQQKDLP TTRSYLKLYT TLPLTKLASF IDPNASEDDV SKLLIRLLCF KHKMRNLVWS 480
KGPSGLEGTF KSGSELDFYI DDDMIHIADT KVSHRYGDFF VRKILKFNDL NRKLKNINI 539 |
Gene Ontology | GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:HAMAP. GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:HAMAP. GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:HAMAP. GO:0003743; F:translation initiation factor activity; IEA:HAMAP. GO:0001731; P:formation of translation preinitiation complex; IEA:HAMAP. GO:0048812; P:neuron projection morphogenesis; IMP:FlyBase. GO:0006446; P:regulation of translational initiation; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |