| Tag | Content |
|---|
| CPLM ID | CPLM-000828 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Guanylate cyclase soluble subunit beta-1 |
Protein Synonyms/Alias | GCS-beta-1; Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit |
Gene Name | Gucy1b3 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 47 | RIIYDDSKTYDLVAA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | |
Sequence Annotation | DOMAIN 421 554 Guanylate cyclase.
METAL 105 105 Iron (heme proximal ligand) (By |
Keyword | cGMP biosynthesis; Complete proteome; Cytoplasm; GTP-binding; Heme; Iron; Lyase; Metal-binding; Nucleotide-binding; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 620 AA |
Protein Sequence | MYGFVNHALE LLVIRNYGPE VWEDIKKEAQ LDEEGQFLVR IIYDDSKTYD LVAAASKVLN 60
LNAGEILQMF GKMFFVFCQE SGYDTILRVL GSNVREFLQN LDALHDHLAT IYPGMRAPSF 120
RCTDAEKGKG LILHYYSERE GLQDIVIGII KTVAQQIHGT EIDMKVIQQR NEECDHTQFL 180
IEEKESKEED FYEDLDRFEE NGTQESRISP YTFCKAFPFH IIFDRNLVVT QCGNAIYRVL 240
PQLQPGNCSL LSVFSLVRPH IDISFHGILS HINTVFVLRS KEGLLDVEKL ECEDELTGAE 300
ISCLRLKGQM IYLPEADSIL FLCSPSVMNL DDLTRRGLYL SDIPLHDATR DLVLLGEQFR 360
EEYKLTQELE ILTDRLQLTL RALEDEKKKT DTLLYSVLPP SVANELRHKR PVPAKRYDNV 420
TILFSGIVGF NAFCSKHASG EGAMKIVNLL NDLYTRFDTL TDSRKNPFVY KVETVGDKYM 480
TVSGLPEPCI HHARSICHLA LDMMEIAGQV QVDGESVQIT IGIHTGEVVT GVIGQRMPRY 540
CLFGNTVNLT SRTETTGEKG KINVSEYTYR CLMSPENSDP LFHLEHRGPV SMKGKKEPMQ 600
VWFLSRKNTG TEETNEEDEN 620 |
Gene Ontology | GO:0008074; C:guanylate cyclase complex, soluble; IEA:Compara. GO:0043231; C:intracellular membrane-bounded organelle; IEA:Compara. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0004383; F:guanylate cyclase activity; IEA:EC. GO:0020037; F:heme binding; IEA:Compara. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0007263; P:nitric oxide mediated signal transduction; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |