CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044316
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 
Protein Synonyms/Alias
  
Gene Name
 BNIP2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
233KTTEVIRKGSITEYTubiquitination[1]
245EYTAAEEKEDGRRWRubiquitination[1]
427VDQELNGKQDEPKNEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 435 AA 
Protein Sequence
MLCGFQEDAT PPPPPRPRRL HRRLPRPEEV GMLSLPPGLL TVSGSAAAAD AVPLRPGDWA 60
GVSTADRGER APLGPAFCDL AVSPTSPAWR GEEDEGAKAS SGDIGSLDYQ EFVVDIESRL 120
RMEGVELKEE WQDEDFPIPL PEDDSIEADI LAITGPEDQP GSLEVNGNKV RKKLMAPDIS 180
LTLDPSDGSV LSDDLDESGE IDLDGLDTPS ENSNEFEWED DLPKPKTTEV IRKGSITEYT 240
AAEEKEDGRR WRMFRIGEQD HRVDMKAIEP YKKVISHGGY YGDGLNAIVV FAVCFMPESS 300
QPNYRYLMDN LFKYVIGTLE LLVAENYMIV YLNGATTRRK MPSLGWLRKC YQQIDRRLRK 360
NLKSLIIVHP SWFIRTLLAV TRPFISSKFS QKIRYVFNLA ELAELVPMEY VGIPECIKQV 420
DQELNGKQDE PKNEQ 435 
Gene Ontology
 GO:0005814; C:centriole; IEA:Compara.
 GO:0031616; C:spindle pole centrosome; IEA:Compara.
 GO:0001824; P:blastocyst development; IEA:Compara.
 GO:0043410; P:positive regulation of MAPK cascade; IEA:Compara.
 GO:0045666; P:positive regulation of neuron differentiation; IEA:Compara.
 GO:0051057; P:positive regulation of small GTPase mediated signal transduction; IEA:Compara.
 GO:0051300; P:spindle pole body organization; IEA:Compara.
 GO:0051146; P:striated muscle cell differentiation; IEA:Compara. 
Interpro
 IPR022181; Bcl2-/adenovirus-E1B.
 IPR001251; CRAL-TRIO_dom. 
Pfam
 PF12496; BNIP2 
SMART
 SM00516; SEC14 
PROSITE
 PS50191; CRAL_TRIO 
PRINTS