UniProt Accession

 Q5VVR7_HUMAN; Q5VVR7 

Genbank Protein ID

 AL135792; AL158212; AL445486; AL451084 

Genbank Nucleotide ID

  

Protein Name

 Transcription factor 7-like 2 

Protein Synonyms/Alias

  

Gene Name

 TCF7L2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
45	ERDLADVKSSLVNES	ubiquitination	[1]
132	ARTYLQMKWPLLDVQ	ubiquitination	[2]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 317 AA 

Protein Sequence

Gene Ontology

 GO:0016055; P:Wnt receptor signaling pathway; IEA:InterPro. 

Interpro

 IPR027397; Catenin_binding_dom.
 IPR013558; CTNNB1-bd_N.
 IPR024940; TCF/LEF. 

Pfam

 PF08347; CTNNB1_binding 

SMART

  

PROSITE

  

PRINTS