CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009214
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Gamma-aminobutyric acid receptor-associated protein 
Protein Synonyms/Alias
 GABA(A) receptor-associated protein 
Gene Name
 Gabarap 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
2******MKFVYKEEHacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
 Involved in apoptosis (By similarity). May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in autophagy (By similarity). 
Sequence Annotation
 REGION 1 22 Interaction with beta-tubulin.
 REGION 36 117 Interaction with GPHN.
 REGION 36 68 Interaction with GABRG2 (Potential).
 LIPID 116 116 Phosphatidylethanolamine amidated glycine  
Keyword
 3D-structure; Apoptosis; Autophagy; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Golgi apparatus; Lipoprotein; Membrane; Microtubule; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 117 AA 
Protein Sequence
MKFVYKEEHP FEKRRSEGEK IRKKYPDRVP VIVEKAPKAR IGDLDKKKYL VPSDLTVGQF 60
YFLIRKRIHL RAEDALFFFV NNVIPPTSAT MGQLYQEHHE EDFFLYIAYS DESVYGL 117 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IEA:Compara.
 GO:0005776; C:autophagic vacuole; ISS:UniProtKB.
 GO:0000421; C:autophagic vacuole membrane; IEA:Compara.
 GO:0044297; C:cell body; IDA:RGD.
 GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.
 GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
 GO:0005764; C:lysosome; IEA:Compara.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005790; C:smooth endoplasmic reticulum; IEA:Compara.
 GO:0006914; P:autophagy; IEA:UniProtKB-KW.
 GO:0008625; P:extrinsic apoptotic signaling pathway via death domain receptors; ISS:UniProtKB.
 GO:0000226; P:microtubule cytoskeleton organization; IEA:Compara.
 GO:0015031; P:protein transport; IMP:RGD. 
Interpro
 IPR004241; Atg8_ubiquitin-like. 
Pfam
 PF02991; Atg8 
SMART
  
PROSITE
  
PRINTS