UniProt Accession

 ARF4_MOUSE; P61750; P36403; Q3TGC2; Q9CXX3 

Genbank Protein ID

 D87901; AK013892; AK081686; AK153011; AK168793 

Genbank Nucleotide ID

 BAA13493.1; BAB29041.1; BAC38292.1; BAE31650.1; BAE40626.1 

Protein Name

 ADP-ribosylation factor 4 

Protein Synonyms/Alias

  

Gene Name

 Arf4 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
142	AISEMTDKLGLQSLR	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. 

Sequence Annotation

 NP_BIND 24 31 GTP (By similarity).
 NP_BIND 67 71 GTP (By similarity).
 NP_BIND 126 129 GTP (By similarity).
 LIPID 2 2 N-myristoyl glycine (Potential).  

Keyword

 Complete proteome; ER-Golgi transport; Golgi apparatus; GTP-binding; Lipoprotein; Myristate; Nucleotide-binding; Protein transport; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 180 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0005525; F:GTP binding; TAS:MGI.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Compara.
 GO:0015031; P:protein transport; TAS:MGI.
 GO:0048678; P:response to axon injury; IEA:Compara.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR. 

Pfam

 PF00025; Arf 

SMART

 SM00177; ARF 

PROSITE

 PS51417; ARF 

PRINTS

 PR00328; SAR1GTPBP.