CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040239
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine-protein kinase ATM 
Protein Synonyms/Alias
  
Gene Name
 Atm 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
160KKMMEVQKKSFEEKYacetylation[1]
161KMMEVQKKSFEEKYDacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 201 AA 
Protein Sequence
XKMVKDMEAL CDAYIILANM DASQWRAQRK GINIPANQPI TKLKNLEDVV VPTMEIKVDP 60
TGEYENLGRD DLRQDAVMQQ VFQMCNTLLQ RNTETRKRKL TICTYKVVPL SQRSGVLEWC 120
TGTVPIGEYL VNSEDGAHRR YRPNDFSANQ CQKKMMEVQK KSFEEKYDTF MTICQNFEPV 180
FRYFCMEKFL DPAVWFEKRL A 201 
Gene Ontology
 GO:0005634; C:nucleus; TAS:MGI.
 GO:0005819; C:spindle; IDA:MGI.
 GO:0004672; F:protein kinase activity; IDA:MGI.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
 GO:0007420; P:brain development; IGI:MGI.
 GO:0000077; P:DNA damage checkpoint; IMP:MGI.
 GO:0006281; P:DNA repair; IDA:MGI.
 GO:0007507; P:heart development; IGI:MGI.
 GO:0016572; P:histone phosphorylation; IEA:InterPro.
 GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; IMP:MGI.
 GO:0042159; P:lipoprotein catabolic process; IGI:MGI.
 GO:0051402; P:neuron apoptotic process; IGI:MGI.
 GO:0048599; P:oocyte development; IMP:MGI.
 GO:0043525; P:positive regulation of neuron apoptotic process; IGI:MGI.
 GO:0090399; P:replicative senescence; IEA:InterPro.
 GO:0010212; P:response to ionizing radiation; IGI:MGI.
 GO:0001756; P:somitogenesis; IGI:MGI.
 GO:0000723; P:telomere maintenance; IEA:InterPro. 
Interpro
 IPR015519; ATM/Tel1.
 IPR011009; Kinase-like_dom.
 IPR000403; PI3/4_kinase_cat_dom. 
Pfam
 PF00454; PI3_PI4_kinase 
SMART
 SM00146; PI3Kc 
PROSITE
 PS50290; PI3_4_KINASE_3 
PRINTS