CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021854
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Squamous cell carcinoma antigen recognized by T-cells 3 
Protein Synonyms/Alias
 SART-3; mSART-3; Tumor-rejection antigen SART3 
Gene Name
 Sart3 
Gene Synonyms/Alias
 Kiaa0156 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
569DWDLAIQKTETRLARacetylation[1]
814GLPFSCTKEELEDICacetylation[2]
957MSNADFAKLLLRK**ubiquitination[3]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 MOTIF 602 618 Nuclear localization signal (Potential).
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 10 10 Phosphoserine (By similarity).
 MOD_RES 852 852 Phosphoserine (By similarity).  
Keyword
 Acetylation; Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Reference proteome; Repeat; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 962 AA 
Protein Sequence
MATTAASSAS EPEVEPQAGP EAEGEEDEAK PAGVQRKVLS GAVAAEAAEA KGPGWDLQRE 60
GASGSDGDEE DAMASSAESS AGEDEWEYDE EEEKNQLEIE RLEEQLSING YDYNCHVELI 120
RLLRLEGELS RVRAARQKMS ELFPLTEELW LEWLHDEISM AMDGLDREHV YELFERAVKD 180
YICPNIWLEY GQYSVGGIGQ KGGLEKVRSV FERALSSVGL HMTKGLAIWE AYREFESAIV 240
EAARLEKVHS LFRRQLAIPL YEMEATFAEY EEWSEEPMPE SVLQSYQKAL GQLEKYKPYE 300
EALLQAEAPR LAEYQAYIDF EMKIGDPARI QLIFERALVE NCLVPDLWIR YSQYLDRQLK 360
VKDLVLSVHS RAVRNCPWTV ALWSRYLLAM ERHGLDHQTI SATFENALSA GFIQATDYVE 420
IWQVYLDYLR RRVDFRQDSS KELEELRSMF TRALEYLQQE VEERFSESGD PSCLIMQSWA 480
RVEARLCNNM QKARELWDSI MTRGNAKYAN MWLEYYNLER AHGDTQHCRK ALHRAVQCTS 540
DYPEHVCEVL LTMERTEGTL EDWDLAIQKT ETRLARVNEQ RMKAAEKEAA LVQQEEEKAE 600
QRKKVRAEKK ALKKKKKTRG ADKRREDEDE ENEWGEEEEE QPSKRRRTEN SLASGEASAM 660
KEETELSGKC LTIDVGPPSK QKEKAASLKR DMPKVAHDSS KDSVTVFVSN LPYSIEEPEV 720
KLRPLFEVCG EVVQIRPIFS NRGDFRGYCY VEFGEEKSAQ QALELDRKIV EGRPMFVSPC 780
VDKSKNPDFK VFRYSTTLEK HKLFISGLPF SCTKEELEDI CKAHGTVKDL RLVTNRAGKP 840
KGLAYVEYEN ESQASQAVMK MDGMTIRENV IKVAISNPPQ RKVPEKPEVR TAPGAPMLPR 900
QMYGARGKGR TQLSLLPRAL QRQGAAPQAE NGPAPGPAVA PSVATEAPKM SNADFAKLLL 960
RK 962 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; ISA:MGI.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; ISA:MGI.
 GO:0006396; P:RNA processing; IEA:InterPro. 
Interpro
 IPR003107; HAT.
 IPR008669; LSM_interact.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF05391; Lsm_interact
 PF00076; RRM_1 
SMART
 SM00386; HAT
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS