CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017586
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Retinol dehydrogenase 13 
Protein Synonyms/Alias
  
Gene Name
 RDH13 
Gene Synonyms/Alias
 PSEC0082; UNQ736/PRO1430 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31HLDLASLKSIREFAAubiquitination[1]
221GKYFDGLKQKAPAPEubiquitination[1]
223YFDGLKQKAPAPEAEubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
 Does not exhibit retinol dehydrogenase (RDH) activity in vitro. 
Sequence Annotation
 NP_BIND 45 51 NAD or NADP (By similarity).
 ACT_SITE 200 200 Proton acceptor (By similarity).
 BINDING 174 174 Substrate (By similarity).  
Keyword
 Alternative splicing; Complete proteome; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 331 AA 
Protein Sequence
MEKCEAAAKD IRGETLNHHV NARHLDLASL KSIREFAAKI IEEEERVDIL INNAGVMRCP 60
HWTTEDGFEM QFGVNHLGHF LLTNLLLDKL KASAPSRIIN LSSLAHVAGH IDFDDLNWQT 120
RKYNTKAAYC QSKLAIVLFT KELSRRLQGS GVTVNALHPG VARTELGRHT GIHGSTFSST 180
TLGPIFWLLV KSPELAAQPS TYLAVAEELA DVSGKYFDGL KQKAPAPEAE DEEVARRLWA 240
ESARLVGLEA PSVREQPLPR 260 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 
Interpro
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom.
 IPR020904; Sc_DH/Rdtase_CS. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.
 PR00080; SDRFAMILY.