CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017850
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tetraspanin-8 
Protein Synonyms/Alias
 Tspan-8 
Gene Name
 Tspan8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
136SDNTDEAKDFQKAMIacetylation[1]
Reference
 [1] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379
Functional Description
  
Sequence Annotation
 CARBOHYD 118 118 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 235 AA 
Protein Sequence
MAGVSSCLKY SMFFFNFLFW VCGTLILGLA IWVRVSKDGK EIITSGDSST NPFIAVNILI 60
AVGSIIMVLG FLGCCGAVKE SRCMLLLFFI GLLLILILQV AAGILGAAFK PEYNRILNET 120
LYENAKLLSD NTDEAKDFQK AMIVFQSEFK CCGLENGAAD WGNNFVEAKE SCQCTGTDCA 180
TYQGSSVYPK TCLSLIKDLF EKNIIIVIGI AFGLAVIEIL GLVFSMVLYC QIGSK 235 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030195; P:negative regulation of blood coagulation; IEA:Compara. 
Interpro
 IPR000301; Tetraspanin.
 IPR018499; Tetraspanin/Peripherin.
 IPR018503; Tetraspanin_CS.
 IPR008952; Tetraspanin_EC2. 
Pfam
 PF00335; Tetraspannin 
SMART
  
PROSITE
 PS00421; TM4_1 
PRINTS
 PR00259; TMFOUR.