UniProt Accession

 MLRM_CHICK; P02612 

Genbank Protein ID

 X06387; Y00983 

Genbank Nucleotide ID

 CAA29684.1; CAB46269.1 

Protein Name

 Myosin regulatory light chain 2, smooth muscle major isoform 

Protein Synonyms/Alias

 MLC-2; DTNB; G1; Isoform L20-A 

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Gallus gallus (Chicken) 

NCBI Taxa ID

 9031 

Lysine Modification

Position	Peptide	Type	References
150	YREAPIDKKGNFNYV	ubiquitination	[1]
151	REAPIDKKGNFNYVE	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). 

Sequence Annotation

 DOMAIN 29 64 EF-hand 1.
 DOMAIN 98 133 EF-hand 2.
 DOMAIN 134 169 EF-hand 3.
 MOD_RES 2 2 N-acetylserine.  

Keyword

 3D-structure; Acetylation; Calcium; Complete proteome; Direct protein sequencing; Metal-binding; Motor protein; Muscle protein; Myosin; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 172 AA 

Protein Sequence

Gene Ontology

 GO:0016460; C:myosin II complex; IEA:Compara.
 GO:0001725; C:stress fiber; IEA:Compara.
 GO:0030018; C:Z disc; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 

Pfam

 PF13499; EF_hand_5 

SMART

 SM00054; EFh 

PROSITE

 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 

PRINTS