CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012888
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Metal transporter CNNM3 
Protein Synonyms/Alias
 Ancient conserved domain-containing protein 3; mACDP3; Cyclin-M3 
Gene Name
 Cnnm3 
Gene Synonyms/Alias
 Acdp3 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
312DPYSDLSKGVLRSRTubiquitination[1]
466SEDYSDTKVRKKTVAubiquitination[1]
497SDDEYKVKISPQLLLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Probable metal transporter (By similarity). 
Sequence Annotation
 DOMAIN 143 294 DUF21.
 DOMAIN 324 385 CBS 1.
 DOMAIN 392 458 CBS 2.
 MOD_RES 667 667 Phosphoserine (By similarity).
 MOD_RES 706 706 Phosphoserine.
 CARBOHYD 73 73 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; CBS domain; Cell membrane; Complete proteome; Glycoprotein; Ion transport; Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 713 AA 
Protein Sequence
MAAAAAAVVG WLGWVLAAFC LGSTAGEAAP APGAGLLNFC TEEDSAPGAG SLRGRAAPEA 60
TLCLRLFCSG LANSSWTWVA AEGAGCPEGG RATEPEEAAA PTGEWRALLR LRAEAGHPRS 120
ALLAVRVEPG GGAAEEAAPP WALGLGAAGL LALAAVARGL QLSALALAPA EVQVLRESGS 180
EAERAAARRL EPARRWAGCA LGALLLLASL AQAALAVLLY GAAGQRAVPA VLGCAGLVFL 240
VGEVLPAAVS GRWALALAPR ALGLSRLAVL LTLPVALPVG QLLELAARPG RLRERVLELA 300
RGGGDPYSDL SKGVLRSRTV EDVLTPLEDC FMLDSGTVLD FSVLASIMQS GHTRIPVYEE 360
ERSNIVDMLY LKDLAIVEPE DCTPLSTITR FYNHPLHFVF NDTKLDAVLE EFKRGKSHLA 420
IVQKVNNEGE GDPFYEVLGL VTLEDVIEEI IKSEILDESE DYSDTKVRKK TVALGAPLKR 480
KEEFSLFKVS DDEYKVKISP QLLLATQRFL SREVDVFSPL RVSEKVLLHL LKHPSVNQEV 540
TFDESNRLAA HHYLYQRSQP VDYFILILQG RVEVEIGKEG LKFENGAFTY YGVSALTAPS 600
SAHQSPVSSR QLIRHDVQPE PADGTRSCTY CPDYTVRALS DLQLIKVTRL QYLNALLATR 660
AQSLPPSPEN AELQAIPGSQ TRLLGDKSRE TAGSTNSRPS IPVEESPGRN PGV 713 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006811; P:ion transport; IEA:UniProtKB-KW. 
Interpro
 IPR000644; Cysta_beta_synth_core.
 IPR002550; DUF21. 
Pfam
 PF01595; DUF21 
SMART
  
PROSITE
 PS51371; CBS 
PRINTS