UniProt Accession

 B7Z4K6_HUMAN; B7Z4K6 

Genbank Protein ID

 AC020934; AK297493 

Genbank Nucleotide ID

 BAH12592.1 

Protein Name

 Deoxyribonuclease-2-alpha 

Protein Synonyms/Alias

 cDNA FLJ51996, highly similar to Deoxyribonuclease-2-alpha (EC 3.1.22.1) 

Gene Name

 DNASE2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
52	AQRGLQYKYLDESSG	ubiquitination	[1, 2]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 305 AA 

Protein Sequence

Gene Ontology

 GO:0004531; F:deoxyribonuclease II activity; IEA:InterPro.
 GO:0006259; P:DNA metabolic process; IEA:InterPro. 

Interpro

 IPR004947; DNase_II. 

Pfam

 PF03265; DNase_II 

SMART

  

PROSITE

  

PRINTS