| Tag | Content |
|---|
| CPLM ID | CPLM-020001 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Actin-related protein 2/3 complex subunit 1A |
Protein Synonyms/Alias | |
Gene Name | Arpc1a |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 179 | YIKEVDEKPASTPWG | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
Sequence Annotation | REPEAT 6 45 WD 1.
REPEAT 50 89 WD 2.
REPEAT 140 179 WD 3.
REPEAT 202 241 WD 4.
REPEAT 244 284 WD 5.
REPEAT 322 365 WD 6. |
Keyword | Actin-binding; Complete proteome; Cytoplasm; Cytoskeleton; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 370 AA |
Protein Sequence | MSLHQFLLEP ITCHAWNRDR TQIALSPNNH EVHIYKKNGS QWTKAHELKE HNGHITGIDW 60
APKSDRIVTC GADRNAYVWS QKDGIWKPTL VILRINRAAT FVKWSPLENK FAVGSGARLI 120
SVCYFESEND WWVSKHIKKP IRSTVLSLDW HPNNVLLAAG SCDFKCRVFS AYIKEVDEKP 180
ASTPWGSKMP FGQLMSEFGG SGTGGWVHGV SFSASGSRLA WVSHDSTVSV ADASKSVQVS 240
TLRTEFLPLL SVSFVSENSV VAAGHDCCPM LFNYDDRGCL TFVSKLDVPK QSIQRNMSAM 300
ERFRNMDKRA TTEDRNTALE TLHQNSITQV SIYEVDKQDC RKFCTTGIDG AMTIWDFKTL 360
ESSIQGLRIM 370 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |