CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036099
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Deoxycytidylate deaminase 
Protein Synonyms/Alias
  
Gene Name
 DCTD 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
131EVIFMSDKYHDSDEAacetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
 ACT_SITE 86 86 Proton donor (By similarity).
 METAL 84 84 Zinc; catalytic (By similarity).
 METAL 110 110 Zinc; catalytic (By similarity).
 METAL 113 113 Zinc; catalytic (By similarity).  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 169 AA 
Protein Sequence
MSEVSCKKRD DYLEWPEYFM AVAFLSAQRS KDPNSQVGAC IVNSENKIVG IGYNGMPNGC 60
SDDVLPWRRT AENKLDTKYP YVCHAELNAI MNKNSTDVKG CSMYVALFPC NECAKLIIQA 120
GIKEVIFMSD KYHDSDEATA ARLLFNMAGV TFRKFIPKCS KIVIDFDSI 169 
Gene Ontology
 GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0008152; P:metabolic process; IEA:GOC. 
Interpro
 IPR016192; APOBEC/CMP_deaminase_Zn-bd.
 IPR002125; CMP_dCMP_Zn-bd.
 IPR015517; Cyt_deaminase.
 IPR016193; Cytidine_deaminase-like.
 IPR016473; dCMP_deaminase. 
Pfam
 PF00383; dCMP_cyt_deam_1 
SMART
  
PROSITE
 PS00903; CYT_DCMP_DEAMINASES 
PRINTS