UniProt Accession

 H32_ARATH; P59226 

Genbank Protein ID

 M35387; M17131; M17130; AC003114; AB024028; AL353995; AL353995; AB011479; CP002684; CP002686; CP002688; CP002688; CP002688; AK117157; AF370577; AY037250; AY039904; AY077654; AY081741; BT003051; BT003162; BT005805; BT006068; AY084316 

Genbank Nucleotide ID

 AAA79889.1; AAA32809.1; AAA32808.1; AAC24084.1; BAA95712.1; CAB89403.1; CAB89404.1; BAB11558.1; AEE28413.1; AEE77308.1; AED91535.1; AED91536.1; AED98043.1; BAC41835.1; AAK49583.1; AAK59851.1; AAK64008.1; AAL76132.1; AAL87394.1; AAO23616.1; AAO24594.1; AAO64207.1; AAP04053.1; AAM60903.1 

Protein Name

 Histone H3.2 

Protein Synonyms/Alias

 Histone H3.1 

Gene Name

 HTR2; HTR3; HTR13; HTR9; HTR1 

Gene Synonyms/Alias

 At1g09200; T12M4.9; At3g27360; K1G2.8; At5g10390; F12B17_260; At5g10400; F12B17_250; At5g65360; MNA5.9 

Created Date

 July 27, 2013 

Organism

 Arabidopsis thaliana (Mouse-ear cress) 

NCBI Taxa ID

 3702 

Lysine Modification

Position	Peptide	Type	References
10	RTKQTARKSTGGKAP	acetylation	[1, 2, 3, 4]
15	ARKSTGGKAPRKQLA	acetylation	[1, 3, 5]
19	TGGKAPRKQLATKAA	acetylation	[1, 3]
24	PRKQLATKAARKSAP	acetylation	[1, 3]
28	LATKAARKSAPATGG	acetylation	[2, 4, 6]

Reference

 [1] Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications.
 Johnson L, Mollah S, Garcia BA, Muratore TL, Shabanowitz J, Hunt DF, Jacobsen SE.
 Nucleic Acids Res. 2004;32(22):6511-8. [PMID: 15598823]
 [2] Arabidopsis GCN5, HD1, and TAF1/HAF2 interact to regulate histone acetylation required for light-responsive gene expression.
 Benhamed M, Bertrand C, Servet C, Zhou DX.
 Plant Cell. 2006 Nov;18(11):2893-903. [PMID: 17085686]
 [3] Distinctive core histone post-translational modification patterns in Arabidopsis thaliana.
 Zhang K, Sridhar VV, Zhu J, Kapoor A, Zhu JK.
 PLoS One. 2007 Nov 21;2(11):e1210. [PMID: 18030344]
 [4] Dynamic landscapes of four histone modifications during deetiolation in Arabidopsis.
 Charron JB, He H, Elling AA, Deng XW.
 Plant Cell. 2009 Dec;21(12):3732-48. [PMID: 20008096]
 [5] In vitro specificities of Arabidopsis co-activator histone acetyltransferases: implications for histone hyperacetylation in gene activation.
 Earley KW, Shook MS, Brower-Toland B, Hicks L, Pikaard CS.
 Plant J. 2007 Nov;52(4):615-26. [PMID: 17877703]
 [6] Lysine acetylation is a widespread protein modification for diverse proteins in Arabidopsis.
 Wu X, Oh MH, Schwarz EM, Larue CT, Sivaguru M, Imai BS, Yau PM, Ort DR, Huber SC.
 Plant Physiol. 2011 Apr;155(4):1769-78. [PMID: 21311030] 

Functional Description

 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. 

Sequence Annotation

 MOD_RES 5 5 N6,N6,N6-trimethyllysine; alternate.
 MOD_RES 5 5 N6,N6-dimethyllysine; alternate.
 MOD_RES 5 5 N6-methyllysine; alternate.
 MOD_RES 10 10 N6,N6,N6-trimethyllysine; alternate.
 MOD_RES 10 10 N6,N6-dimethyllysine; alternate.
 MOD_RES 10 10 N6-acetyllysine; alternate.
 MOD_RES 10 10 N6-methyllysine; alternate.
 MOD_RES 11 11 Phosphoserine.
 MOD_RES 12 12 Phosphothreonine.
 MOD_RES 15 15 N6-acetyllysine.
 MOD_RES 19 19 N6-acetyllysine; alternate.
 MOD_RES 19 19 N6-methyllysine; alternate.
 MOD_RES 24 24 N6-acetyllysine; alternate.
 MOD_RES 24 24 N6-methyllysine; alternate.
 MOD_RES 28 28 N6,N6,N6-trimethyllysine; alternate.
 MOD_RES 28 28 N6,N6-dimethyllysine; alternate.
 MOD_RES 28 28 N6-methyllysine; alternate.
 MOD_RES 29 29 Phosphoserine.
 MOD_RES 37 37 N6,N6,N6-trimethyllysine; alternate.
 MOD_RES 37 37 N6,N6-dimethyllysine; alternate.
 MOD_RES 37 37 N6-methyllysine; alternate.  

Keyword

 3D-structure; Acetylation; Chromosome; Complete proteome; DNA-binding; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 136 AA 

Protein Sequence

Gene Ontology

 GO:0000786; C:nucleosome; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR009072; Histone-fold.
 IPR007125; Histone_core_D.
 IPR000164; Histone_H3. 

Pfam

 PF00125; Histone 

SMART

 SM00428; H3 

PROSITE

 PS00322; HISTONE_H3_1
 PS00959; HISTONE_H3_2 

PRINTS

 PR00622; HISTONEH3.