| Tag | Content |
|---|
| CPLM ID | CPLM-014961 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | NADH-cytochrome b5 reductase-like |
Protein Synonyms/Alias | |
Gene Name | CYB5RL |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 55 | WEAAQASKDRSLLRG | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). |
Sequence Annotation | DOMAIN 19 55 Oxidoreductase-like.
DOMAIN 75 177 FAD-binding FR-type.
NP_BIND 157 172 FAD (By similarity).
NP_BIND 182 214 FAD (By similarity). |
Keyword | Alternative splicing; Complete proteome; FAD; Flavoprotein; NAD; Oxidoreductase; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 315 AA |
Protein Sequence | MMAEREEDDD TEEAWMQLRP TEPLPSQCCG SGCSPCVFDL YHRDLARWEA AQASKDRSLL 60
RGPESQSCPS KLNPETFVAF CIIAMDRLTK DTYRVRFALP GNSQLGLRPG QHLILRGIVD 120
DLEIQRAYTP ISPANAEGYF EVLIKCYQMG LMSRYVESWR VGDTAFWRGP FGDFFYKPNQ 180
YGELLLLAAG TGLAPMVPIL QSITDNENDE TFVTLVGCFK TFESIYLKTF LQEQARFWNV 240
RTFFVLSQES SSEQLPWSYQ EKTHFGHLGQ DLIKELVSCC RRKPFALVCG SAEFTKDIAR 300
CLLCAGLTED SYFLF 315 |
Gene Ontology | GO:0004128; F:cytochrome-b5 reductase activity, acting on NAD(P)H; IEA:EC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |