CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030338
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Plexin B1 
Protein Synonyms/Alias
  
Gene Name
 Plxnb1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1508QALRDYKKVQIQLENubiquitination[1]
1839ALVPCLTKHILRENQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Disulfide bond; Membrane; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2119 AA 
Protein Sequence
MSVLGPVLLQ VFWAGCVVTL RSPLPAAFTA NGTHLQHLAR DPTTGTLYVG ATNFLFQLSP 60
GLQLEAVVST GPVNDSRDCL PPVIPDECPQ AQPTNNPNQL LLVSPEALVV CGSIHQGICE 120
LRSLGQIRQL LLRPERPGDT QYVAANDPAV STVGLVAQGL VGEPLLFVGR GYTSRGVGGG 180
IPPITTRALR PPDPQAAFSY EETAKLAVGR LSEYSHHFVS AFVRGASAYF LFLRRDLKAP 240
SRAFRAYVSR VCLQDQHYYS YVELPLACQG GRYGLIQAAA VATSKEVARG DVLFAAFSSV 300
APPTVDWPLS ASTGASGTSV LCAFPLDEVD QLANYTRDAC YTREGRAENG TKVADIAYDV 360
LSDCAQLPVD TPDAFPCGSD HTPSPMVSCV PLEATPILEL PGVQLTAVAV TMEDGHTIAF 420
LGDSQGQLHR VYLGPGRSAA PYSKQSIQPG SPVNRDLTFD GTFEHLYVAT QTTLVKVPVA 480
PCAQHLDCDS CLAHRDPYCG WCVLLGRCSR RSECSRDQGP EQWLWSFQPE LGCLRVVAVS 540
PANISREERR EVFLSVPGLP SLWPGESYFC YFGDQQSPAL LTSSGVMCPS PDPSEAPVLQ 600
RGADHISVNV ELRFGAVVIA STSLSFYDCV AVTASSPSAP CRACVSSRWG CNWCVWQQLC 660
THKASCDAGP MVASQQSPLL PLIPPARDEL TPFPPTVPQT TVTPTPNSFP IEPRAPSTAS 720
DVLPGAKPSR LSLWGPWAGP GPILSPTSTE SPLHEKPLPP DPPTIPGTTV PAPTGLGPST 780
TPEDLLASYP FPSDAAAVSP AEPGPEALPS MVALDQPPGT VPDTTFPGAP GSMKPVLDWL 840
TKGGGELPEA DEWMGGDTPA FSTSTLLSGD GDSAEHEGPP APLILLSSLD YQYDTPGLWE 900
LGEVNQRVSS CPCVETVQGS LLIPVHVERE VQLRGRNLWL FQDGPRSSEC VLELGSREVA 960
VEAQVECAPP PDVWCHIKCQ QHQFSYEALK PELQVGLFLR WAGGLRVDSA DGLHVVLYDC 1020
SVGHGDCSRC QTAMPQYDCV WCEGERPRCV AREACNEAET VATQCPAPLI HSVDPLTGPI 1080
DGGTRVTIRG SNLGQHVQDV LDMVRVAGVP CAVDAGEYDV SSSLVCITGA SGEEVTGTVA 1140
VEVPGRGHGV SEFSFAYQDP KVHSIFPARG PRAGGTRLTL HGSKLLTGRL EDIRVVVGDQ 1200
PCHLLLEQQS EQLHCETGPY PVPAELPVTV LFGATERRLQ HGQFKYTSDP NVTSVGPSKS 1260
FFSGGREIWV RGQDLDVVQR PRIRVTVVPR QHGQGLAQKQ HVVPEKFEEP CLVNSSHLLM 1320
CRTPALPGPP WDSGVQVEFI LDNMVFDFAA LSPTPFSYEA DPTLRSLNPE DPSTPFRHKP 1380
GSVFSVEGEN LDLAMSKEEV VAMIGDGPCV VKTLTRNHLY CEPPVEQPLP HPHALREAPD 1440
ALPEFTVQMG NLRFSLGHVQ YDGESPVAFP VAAQVGLGVG TSLLALGVII IVLIYRRKSK 1500
QALRDYKKVQ IQLENLESSV RDRCKKEFTD LMTEMTDLTS DLLGSGIPFL DYKVYAERFF 1560
FPGYRESPLH RDLGVPDSRR PTVEQGLGQL SNLLNSKLFL TKFIHTLESQ RTFSARDRAY 1620
VASLLTVALH GKLEYFTDIL RTLLSDLVAQ YVAKNPKLML RRTETVVEKL LTNWMSICLY 1680
TFVRDSVGEP LYMLFRGIKH QVDKGPVDSV TGKAKYTLND NRLLREDVEY RPLTLNALLA 1740
VGPGAGEAQC VPVKVLDCDT ISQAKEKMLD QLYKGVPLAQ RPDSCTLDVE WRSGVAGHLI 1800
LSDEDVTSEL QGLWRRLNTL QHYKVPDGAT VALVPCLTKH ILRENQDYVP GERTPMLEDV 1860
DEGGIRPWHL VKPSDEPEPP RPRRGSLRGG ERERAKAIPE IYLTRLLSMK GTLQKFVDDL 1920
FQVILSTSRP VPLAVKYFFD LLDEQAQQHG ISDQDTIHIW KTNSLPLRFW INIIKNPQFV 1980
FDVQTSDNMD AVLLVIAQTF MDACTLADHK LGRDSPINKL LYARDIPRYK QMVERYYADI 2040
RQTVPASDQE MNSVLAELSR NCSADLGARV ALHELYKYIN KYYDQIITAL EEDGTAQKMQ 2100
LGYRLQQIAA AVENKVTDL 2119 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0004872; F:receptor activity; IEA:InterPro.
 GO:0050772; P:positive regulation of axonogenesis; IGI:MGI.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR015716; CD2_adhesion_molc.
 IPR013783; Ig-like_fold.
 IPR014756; Ig_E-set.
 IPR002909; IPT_TIG_rcpt.
 IPR003659; Plexin-like.
 IPR016201; Plexin-like_fold.
 IPR013548; Plexin_cytoplasmic_RasGAP_dom.
 IPR002165; Plexin_repeat.
 IPR008936; Rho_GTPase_activation_prot.
 IPR001627; Semaphorin/CD100_Ag.
 IPR015943; WD40/YVTN_repeat-like_dom. 
Pfam
 PF08337; Plexin_cytopl
 PF01437; PSI
 PF01403; Sema
 PF01833; TIG 
SMART
 SM00429; IPT
 SM00423; PSI
 SM00630; Sema 
PROSITE
 PS51004; SEMA 
PRINTS