UniProt Accession

 RNZ_BACSU; P54548 

Genbank Protein ID

 D84432; AL009126 

Genbank Nucleotide ID

 BAA12617.1; CAB14316.1 

Protein Name

 Ribonuclease Z 

Protein Synonyms/Alias

 RNase Z; tRNA 3 endonuclease; tRNase Z 

Gene Name

 rnz 

Gene Synonyms/Alias

 yqjK; BSU23840 

Created Date

 July 27, 2013 

Organism

 Bacillus subtilis (strain 168) 

NCBI Taxa ID

 224308 

Lysine Modification

Position	Peptide	Type	References
201	NDFLEPPKKGRSVVF	acetylation	[1]

Reference

 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 

Functional Description

 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. 

Sequence Annotation

 ACT_SITE 67 67 Proton acceptor (Potential).
 METAL 63 63 Zinc 1; catalytic.
 METAL 65 65 Zinc 1; catalytic.
 METAL 67 67 Zinc 2; catalytic.
 METAL 68 68 Zinc 2; catalytic.
 METAL 140 140 Zinc 1; catalytic.
 METAL 211 211 Zinc 1; catalytic.
 METAL 211 211 Zinc 2; catalytic.
 METAL 269 269 Zinc 2; catalytic.  

Keyword

 3D-structure; Complete proteome; Endonuclease; Hydrolase; Metal-binding; Nuclease; Reference proteome; tRNA processing; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 307 AA 

Protein Sequence

Gene Ontology

 GO:0042781; F:3'-tRNA processing endoribonuclease activity; IEA:HAMAP.
 GO:0008270; F:zinc ion binding; IEA:HAMAP.
 GO:0042779; P:tRNA 3'-trailer cleavage; IEA:InterPro. 

Interpro

 IPR001279; Beta-lactamas-like.
 IPR013471; RNase_Z. 

Pfam

  

SMART

 SM00849; Lactamase_B 

PROSITE

  

PRINTS