| Tag | Content |
|---|
| CPLM ID | CPLM-011537 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Probable ATP-dependent RNA helicase Dbp45A |
Protein Synonyms/Alias | DEAD box protein 45A |
Gene Name | Dbp45A |
Gene Synonyms/Alias | CG12759 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 497 | TQEDTPTKPLKRLNK | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Probable ATP-binding RNA helicase. |
Sequence Annotation | DOMAIN 38 209 Helicase ATP-binding.
DOMAIN 237 386 Helicase C-terminal.
NP_BIND 51 58 ATP (By similarity).
MOTIF 7 35 Q motif.
MOTIF 157 160 DEAD box. |
Keyword | ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome; RNA-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 521 AA |
Protein Sequence | MQRKEANPFQ ILGLRPWLVK QLTKLGLKGA TPIQQKCIPA ILAGQDCIGA AKTGSGKTFA 60
FALPILERLS EEPVSHFALV LTPTHELAYQ ISEQFLVAGQ AMGVRVCVVS GGTDQMVESQ 120
KLMQRPHIVV AMPGRLADHL TGCDTFSFDN LKYLVVDEAD RMLNGDFDES LSIIERCLPK 180
TRQNLFFSAT MKDFIKESSI FPIASDCFEW SQDSDVATVE TLDQRYLLCA DYDRDMVLIE 240
ALRKYREENE NANVMIFTNT KKYCQLLSMT LKNMEIDNVC LHGFMRQKER VAALSRFKSN 300
QIRTLIATDV AARGLDIPSV ELVMNHMLPR TPKEYIHRVG RTARAGRKGM SISIFRFPRD 360
LELLAAIEEE INTKLTEHPI DQRMVERIFM QVNVTRRESE MQLDNNDFDE RAQNYRRKTW 420
IMEGKDPDQM EALYRKKQKD KLREIRRKRK LQHAEPAASE EGKALLQDER FKSVDSARFE 480
KKGKGRSRAT QEDTPTKPLK RLNKEKPVAQ KGRADVKKDK A 521 |
Gene Ontology | GO:0005634; C:nucleus; IC:FlyBase. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004004; F:ATP-dependent RNA helicase activity; ISS:FlyBase. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |