CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043680
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase RNF34 
Protein Synonyms/Alias
  
Gene Name
 RNF34 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
2******MKAGATSMWubiquitination[1, 2]
83HVCCDCKKDFCSVCSubiquitination[1]
121QLMRLKVKDLRQYLIubiquitination[1]
273GMSVRQLKEILARNFubiquitination[1]
295EKWELVEKVNRLYKEubiquitination[2]
301EKVNRLYKENEENQKubiquitination[1]
308KENEENQKSYGERLQubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 507 AA 
Protein Sequence
MKAGATSMWA SCCGLLNEVM GTGAVRGQQS AFAGATGPFR FTPNPEFSTY PPAATEGPNI 60
VCKACGLSFS VFRKKHVCCD CKKDFCSVCS VLQENLRRCS TCHLLQETAF QRPQLMRLKV 120
KDLRQYLILR NIPIDTCREK EDLVDLVLCH HGLGSEDDMD TSSLNSSRSQ TSSFFTRSFF 180
SNYTAPSATM SSFQGELMDG DQTSRSGVPA QVQSEITSAN TEDDDDDDDE DDDDEEENAE 240
DRNPGLSKER VRASLSDLSS LDDVEGMSVR QLKEILARNF VNYSGCCEKW ELVEKVNRLY 300
KENEENQKSY GERLQLQDEE DDSLCRICMD AVIDCVLLEC GHMVTCTKCG KRMRMSSCKG 360
RLRNGPESSA VTIQKDQRKV SAHSSPKRVV EQLLPWKDLQ NGIALWSVVP RSKWKIKALI 420
FVKSLPSQSP PRIYILILGL TQFLQEFFFY LPKLDTHRHL GYELLTAFLG DLLAVPQVNM 480
TDVSTAFEEG QALISDLIAV CREEIVM 507 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR011011; Znf_FYVE_PHD.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00184; RING 
PROSITE
  
PRINTS