CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010379
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Phosphoglycerate kinase 
Protein Synonyms/Alias
  
Gene Name
 pgk 
Gene Synonyms/Alias
 MPN_429; MP412 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
28ADLNVPMKDGVITDNacetylation[1]
46LASLDTIKYLLGHNCacetylation[1]
88SALQNLLKNTKVHFCacetylation[1]
134NEAGEVVKHESKNNAacetylation[1]
174ASNAGIAKYIKNSCIacetylation[1]
201RLINNPPKPFVVVLGacetylation[1]
268KQILDSDKDKKIVLGacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
  
Sequence Annotation
 NP_BIND 365 368 ATP (By similarity).
 REGION 22 24 Substrate binding (By similarity).
 REGION 60 63 Substrate binding (By similarity).
 BINDING 37 37 Substrate (By similarity).
 BINDING 122 122 Substrate (By similarity).
 BINDING 164 164 Substrate (By similarity).
 BINDING 215 215 ATP (By similarity).
 BINDING 338 338 ATP (By similarity).  
Keyword
 ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase; Nucleotide-binding; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 409 AA 
Protein Sequence
MVDFKTVQAF DFQGKTVVLR ADLNVPMKDG VITDNERILA SLDTIKYLLG HNCKIVLLSH 60
LSRVKSLDDK KGKKSLQPVA SALQNLLKNT KVHFCPENTG DKVKVAVNQL PLGEILVLEN 120
TRYCDVNEAG EVVKHESKNN AELAQFWASL GDIFVNDAFG TAHRRHASNA GIAKYIKNSC 180
IGLLMERELI NLYRLINNPP KPFVVVLGGA KVSDKLQVVN NLFKIADHIL IGGGMVNTFL 240
KALGNEVGTS LVEEDLVQTA KQILDSDKDK KIVLGVDQML HASFKDEPGV ECVVAPQWPA 300
ELQGFMSLDV GSKTVALFSS YLAKAKTIFW NGPMGVFEFS NYAQGTLAIG KAIAQNQQAF 360
SVIGGGDSAA AAKQLQIADQ FSFISTGGGA SLALIGGEEL VGISDIQKK 409 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004618; F:phosphoglycerate kinase activity; IEA:HAMAP.
 GO:0006096; P:glycolysis; IEA:HAMAP. 
Interpro
 IPR001576; Phosphoglycerate_kinase.
 IPR015901; Phosphoglycerate_kinase_C.
 IPR015911; Phosphoglycerate_kinase_CS.
 IPR015824; Phosphoglycerate_kinase_N. 
Pfam
 PF00162; PGK 
SMART
  
PROSITE
 PS00111; PGLYCERATE_KINASE 
PRINTS
 PR00477; PHGLYCKINASE.