CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030186
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 cDNA, FLJ94229, highly similar to Homo sapiens heterogeneous nuclear ribonucleoprotein L (HNRPL),mRNA 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
31GRAPKRLKTDNAGDQubiquitination[1]
198QRIVIFRKNGVQAMVubiquitination[1]
217VQSAQRAKASLNGADubiquitination[1]
238TLKIEYAKPTRLNVFubiquitination[1]
271DPGSNPNKRQRQPPLubiquitination[1]
424KLNVCVSKQPAIMPGubiquitination[1]
502VKRPSSVKVFSGKSEubiquitination[1]
537FLNHYQMKNPNGPYPubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Ribonucleoprotein; Viral nucleoprotein; Virion. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 558 AA 
Protein Sequence
MVKMAAAGGG GGGGRYYGGG SEGGRAPKRL KTDNAGDQHG GGGGGGGGAG AAGGGGGGEN 60
YDDPHKTPAS PVVHIRGLID GVVEADLVEA LQEFGPISYV VVMPKKRQAL VEFEDVLGAC 120
NAVNYAADNQ IYIAGHPAFV NYSTSQKISR PGDSDDSRSV NSVLLFTILN PIYSITTDVL 180
YTICNPCGPV QRIVIFRKNG VQAMVEFDSV QSAQRAKASL NGADIYSGCC TLKIEYAKPT 240
RLNVFKNDQD TWDYTNPNLS GQGDPGSNPN KRQRQPPLLG DHPAEYGGPH GGYHSHYHDE 300
GYGPPPPHYE GRRMGPPVGG HRRGPSRYGP QYGHPPPPPP PPEYGPHADS PVLMVYGLDQ 360
SKMNCDRVFN VFCLYGNVEK VKFMKSKPGS AMVEMADGYA VDRAITHLNN NFMFGQKLNV 420
CVSKQPAIMP GQSYGLEDGS CSYKDFSESR NNRFSTPEQA AKNRIQHPSN VLHFFNAPLE 480
VTEENFFEIC DELGVKRPSS VKVFSGKSER SSSGLLEWES KSDALETLGF LNHYQMKNPN 540
GPYPYTLKLC FSTAQHAS 558 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006397; P:mRNA processing; IEA:InterPro. 
Interpro
 IPR006536; HnRNP-L_PTB.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
  
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS