UniProt Accession

 CRIP1_MOUSE; P63254; P04006; Q3THF0 

Genbank Protein ID

 M13018; AF450245; AK003075; AK008269; AK012068; AK168305; BC031922 

Genbank Nucleotide ID

 AAA37458.1; AAM97585.1; BAB22550.1; BAB25566.1; BAB28006.1; BAE40246.1; AAH31922.1 

Protein Name

 Cysteine-rich protein 1 

Protein Synonyms/Alias

 CRP-1; Cysteine-rich intestinal protein; CRIP 

Gene Name

 Crip1 

Gene Synonyms/Alias

 Crip 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
9	PKCPKCDKEVYFAER	ubiquitination	[1]
22	ERVTSLGKDWHRPCL	acetylation	[2, 3]
49	GHAEHEGKPYCNHPC	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337] 

Functional Description

 Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein. 

Sequence Annotation

 DOMAIN 2 63 LIM zinc-binding.
 MOD_RES 9 9 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; LIM domain; Metal-binding; Reference proteome; Zinc. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 77 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0003680; F:AT DNA binding; ISS:UniProtKB.
 GO:0008301; F:DNA binding, bending; ISS:UniProtKB.
 GO:0042277; F:peptide binding; ISS:UniProtKB.
 GO:0008270; F:zinc ion binding; ISS:UniProtKB.
 GO:0071236; P:cellular response to antibiotic; ISS:UniProtKB.
 GO:0071493; P:cellular response to UV-B; ISS:UniProtKB.
 GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; ISS:UniProtKB.
 GO:0010043; P:response to zinc ion; ISS:UniProtKB. 

Interpro

 IPR001781; Znf_LIM. 

Pfam

 PF00412; LIM 

SMART

 SM00132; LIM 

PROSITE

 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2 

PRINTS