CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017507
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Programmed cell death protein 7 
Protein Synonyms/Alias
 ES18; hES18 
Gene Name
 PDCD7 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
280EIDRWRVKCVQEVEEubiquitination[1, 2]
295KKREQELKAAADGVLubiquitination[1]
336RKEAAARKGVCPPASubiquitination[1]
361RLRKLIKKRSELYEAubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
 Promotes apoptosis when overexpressed (By similarity). 
Sequence Annotation
  
Keyword
 Apoptosis; Coiled coil; Complete proteome; Nucleus; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 485 AA 
Protein Sequence
MALPPFFGQG RPGPPPPQPP PPAPFGCPPP PLPSPAFPPP LPQRPGPFPG ASAPFLQPPL 60
ALQPRASAEA SRGGGGAGAF YPVPPPPLPP PPPQCRPFPG TDAGERPRPP PPGPGPPWSP 120
RWPEAPPPPA DVLGDAALQR LRDRQWLEAV FGTPRRAGCP VPQRTHAGPS LGEVRARLLR 180
ALRLVRRLRG LSQALREAEA DGAAWVLLYS QTAPLRAELA ERLQPLTQAA YVGEARRRLE 240
RVRRRRLRLR ERAREREAER EAEAARAVER EQEIDRWRVK CVQEVEEKKR EQELKAAADG 300
VLSEVRKKQA DTKRMVDILR ALEKLRKLRK EAAARKGVCP PASADETFTH HLQRLRKLIK 360
KRSELYEAEE RALRVMLEGE QEEERKRELE KKQRKEKEKI LLQKREIESK LFGDPDEFPL 420
AHLLEPFRQY YLQAEHSLPA LIQIRHDWDQ YLVPSDHPKG NFVPQGWVLP PLPSNDIWAT 480
AVKLH 485 
Gene Ontology
 GO:0005689; C:U12-type spliceosomal complex; IDA:HGNC.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
 GO:0006917; P:induction of apoptosis; ISS:HGNC.
 GO:0051384; P:response to glucocorticoid stimulus; ISS:HGNC.
 GO:0008380; P:RNA splicing; IC:HGNC. 
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS