| Tag | Content |
|---|
| CPLM ID | CPLM-007573 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ribosomal RNA large subunit methyltransferase G |
Protein Synonyms/Alias | 23S rRNA m2G1835 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase RlmG |
Gene Name | rlmG |
Gene Synonyms/Alias | ygjO; b3084; JW5513 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 95 | GIDESSVKFLDSTAD | acetylation | [1] | | 349 | RHLDYFHKLKKIFGN | acetylation | [1] | | 351 | LDYFHKLKKIFGNCT | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. |
Sequence Annotation | |
Keyword | 3D-structure; Complete proteome; Cytoplasm; Methyltransferase; Reference proteome; rRNA processing; S-adenosyl-L-methionine; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 378 AA |
Protein Sequence | MSHLDNGFRS LTLQRFPATD DVNPLQAWEA ADEYLLQQLD DTEIRGPVLI LNDAFGALSC 60
ALAEHKPYSI GDSYISELAT RENLRLNGID ESSVKFLDST ADYPQQPGVV LIKVPKTLAL 120
LEQQLRALRK VVTSDTRIIA GAKARDIHTS TLELFEKVLG PTTTTLAWKK ARLINCTFNE 180
PQLADAPQTV SWKLEGTDWT IHNHANVFSR TGLDIGARFF MQHLPENLEG EIVDLGCGNG 240
VIGLTLLDKN PQAKVVFVDE SPMAVASSRL NVETNMPEAL DRCEFMINNA LSGVEPFRFN 300
AVLCNPPFHQ QHALTDNVAW EMFHHARRCL KINGELYIVA NRHLDYFHKL KKIFGNCTTI 360
ATNNKFVVLK AVKLGRRR 378 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0052916; F:23S rRNA (guanine(1835)-N(2))-methyltransferase activity; IDA:EcoCyc. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0070475; P:rRNA base methylation; IMP:EcoCyc. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |