CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001671
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Quinone oxidoreductase-like protein 1 
Protein Synonyms/Alias
 Protein 4P11; Quinone oxidoreductase homolog 1; QOH-1; Zeta-crystallin homolog 
Gene Name
 CRYZL1 
Gene Synonyms/Alias
 4P11 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
48ALSQINTKLLAEMKMubiquitination[1]
56LLAEMKMKKDLFPVGubiquitination[1]
57LAEMKMKKDLFPVGRubiquitination[1]
113HEHYLVHKPEKVTWTubiquitination[1]
116YLVHKPEKVTWTEAAubiquitination[1]
171LAHHRGAKVISTACSubiquitination[1]
182TACSLEDKQCLERFRubiquitination[1]
231AGVRLYSKDDEPAVKubiquitination[1]
305GKYLCILKDVMEKLSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; NADP; Oxidoreductase; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 349 AA 
Protein Sequence
MKGLYFQQSS TDEEITFVFQ EKEDLPVTED NFVKLQVKAC ALSQINTKLL AEMKMKKDLF 60
PVGREIAGIV LDVGSKVSFF QPDDEVVGIL PLDSEDPGLC EVVRVHEHYL VHKPEKVTWT 120
EAAGSIRDGV RAYTALHYLS HLSPGKSVLI MDGASAFGTI AIQLAHHRGA KVISTACSLE 180
DKQCLERFRP PIARVIDVSN GKVHVAESCL EETGGLGVDI VLDAGVRLYS KDDEPAVKLQ 240
LLPHKHDIIT LLGVGGHWVT TEENLQLDPP DSHCLFLKGA TLAFLNDEVW NLSNVQQGKY 300
LCILKDVMEK LSTGVFRPQL DEPIPLYEAK VSMEAVQKNQ GRKKQVVQF 349 
Gene Ontology
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0050661; F:NADP binding; NAS:UniProtKB.
 GO:0003960; F:NADPH:quinone reductase activity; NAS:UniProtKB.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0042375; P:quinone cofactor metabolic process; NAS:UniProtKB. 
Interpro
 IPR013149; ADH_C.
 IPR013154; ADH_GroES-like.
 IPR002085; ADH_SF_Zn-type.
 IPR011032; GroES-like.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF08240; ADH_N
 PF00107; ADH_zinc_N 
SMART
  
PROSITE
 PS01162; QOR_ZETA_CRYSTAL 
PRINTS