CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035526
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Ttn 
Protein Synonyms/Alias
  
Gene Name
 Ttn 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
181KVVVAADKAKEQELRacetylation[1]
417HVVPKAVKPVVIQAPacetylation[1]
1113SQLERLYKPVFVLKPacetylation[1]
1119YKPVFVLKPASFKCLacetylation[1]
1218IKPAFVEKLKNVNIKacetylation[1]
1257SDIIVPHKYPRIRIEacetylation[1]
1354EEGDLYDKEKQQKPFacetylation[1]
1359YDKEKQQKPFFKKKLacetylation[1]
1400VEWLHDGKPLEAANRacetylation[1]
1439ITCRATNKYGTDHTSacetylation[1]
1583GVTEHKVKLEIQQREacetylation[1]
1603LRRAPEPKPEFHVHEacetylation[1]
2124TKAVLECKVSVPDVTacetylation[1]
2143YLNDEQIKPDDRVQSacetylation[1]
2236IKPSSKYKIEAHGKIacetylation[1]
2349DIGEYTYKVATSKTSacetylation[1]
2487VPVKWFHKNVEIKPSacetylation[1]
2492FHKNVEIKPSDKHRLacetylation[1]
2722IEFRKHIKDIKVLEKacetylation[1]
2725RKHIKDIKVLEKKRAacetylation[1]
2818KEVQVIEKQRAVVEFacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 5184 AA 
Protein Sequence
RSVSPAGRIS TSPIRSVKSP LLIRKTQTTT VATGPEVPPP WKQEGYVASS TEAEMRETTM 60
TSSTQIRREE RWEGRYGVQE QVTISGAAGT AASVSARSSF TAEAVTTGAK EVKQETDKSA 120
AVATVVAAVD MARVREPVIS AVEQTAQRTT TTAVHVQPAQ KQMRKEAEKT AVTKVVVAAD 180
KAKEQELRLR TREEIITKQE QTHIAHEQIR KETEKAFVPK VVISATKAKE QETRITGEIT 240
TKQEQKRITQ ETITKETRKT VVPKVIVATP KIKEQDVVSR SREAITTKRD QVQITQEKKR 300
KETETTALST IAVATTKAKE QETVLRSREA MTTRQEHIQV THGKVGVGKK AEAVATVVAA 360
VDQARVREPR EPRHVEESYS QQTTLEYGYK EHISATKVPE QPQRPASEPH VVPKAVKPVV 420
IQAPSETHIK ATDQVGMHIS SQVKKTTDIS TERLVHVDKR PRTASPHFTV SKISVPKTEH 480
GYEASIAGSA IATLQKELST TSSTQKITKS VKAPTVKPGE TRVRAEPTPS PKFPFADVPA 540
PDTYKSQAGI EVKKEVGVSI SGSTVREEQF ELLRGREAKV TETARVPAPA EVPVTPPTLV 600
SGLKNVTVVE GESVTLECHI SGYPSPKVTW YREDYQIESS IDFQITFQSG IARLMIREAF 660
AEDSGRFTCS AVNEAGTVST SCYLAVQVSE EFDKETTLTE KFTTEEKRFV ESRDVVMTDT 720
SITEEQAGPG EPAAPFFISK PVVQKLVEGG SVVFECQIGG NPKPHVYWKK SGVPLTTGYR 780
YKVSYNKQTG ECRLVISMTF ADDAGEYTIV IRNKHGETSA SASLLEEADY EALIKSQQET 840
LYQTQMSTFI QEPKVGEIAP GFAYSEYEKE YEKEQALIRK KMAKDTVMVR TFVEDQEFHI 900
SSFEERLIKE IEYRIIKTTL EELLEEDGEE RMAVDISESE AVESGFDIRI KNYRILEGMG 960
VTFHCKMSGY PLPKIAWYKD GKRIRRGERY QMDFLQDGRA SLRIPVVLPE DEGIYTAFAS 1020
NIKGNAICSG KLYVEPAAPF SAPTYMPTPE AVSRIRSVSP RSVSRSPIRI SPAMSPARMS 1080
PARMSPARMS PARMSPGRRL EETDESQLER LYKPVFVLKP ASFKCLEGQT ARFDLKVVGR 1140
PMPETFWFHN GQQIVNDYTH KVVIKEDGTQ SLIIVPALPS DSGEWTVVAQ NRAGKSTISV 1200
TLTVEAVEHQ IKPAFVEKLK NVNIKEGSRL EMKVRATGNP NPDIVWLKNS DIIVPHKYPR 1260
IRIEGTKGEA ALKIDSTISQ DSAWYTATAI NKAGRDTTRC KVNIEVEFAE PEPERRLIIP 1320
RGTYRAKEIS APELEPLHLR YGQEQWEEGD LYDKEKQQKP FFKKKLTSLR LKRFGPAHFE 1380
CRLTPIGDPT MVVEWLHDGK PLEAANRLRL INEFGYCSLD YEAAYSRDSG VITCRATNKY 1440
GTDHTSATLI VKDEKSLVEE SQLPEGKKGL QRIEELERMA HEGALTGVTT DQKEKQKPDI 1500
VLFPEPVRVL EGETARFRCR VTGYPQPKVN WYLNGQLIRK SKRFRVRYDG IHYLDIVDCK 1560
SYDTGEVKVT AENPEGVTEH KVKLEIQQRE DFRSVLRRAP EPKPEFHVHE PGKLQFEVQK 1620
VDRPVDTGET KEVVKLKRAE RITHEKVSEE SEELRSKFKR RTEEGYYEAI TAVELKSRKK 1680
DESYEELLKK TKDELLHWTK ELTEEEKKAL AEEGKVTIPT FKPERIELSP SMEAPKIFER 1740
IQSQTVGQGS DAHFRVRVVG KPDPECEWYK NGVKIERSDR IYWYWPEDNV CELVIRDVTA 1800
EDSASIMVKA INIAGETSSH AFLLVQAKQL ITFTQELQDV VAKEKDTMAT FECETSEPFV 1860
KVKWYKDGIE VHAGDKYRMH SDRKVHFLSV LTIDTSDAED YSCVLVEDEN IKTTAKLIVE 1920
GAVVEFVKEL QDIEVPESYS GELECIISPE NIEGKWYHND VELKSNGKYS ITSRRGRQNL 1980
TVKDVTKEDQ GEYCFVVDGK KTTCKLKMKP RPIAILQGLS DQKVCEGDIV QLEVKVSLEN 2040
VEGVWMKDGQ EVQHSDRVHI VIDKQSHMLL IEDMTKEDAG NYSFTIPALG LSTSGNVSVY 2100
SVDVITPLKD VNVIEGTKAV LECKVSVPDV TSVKWYLNDE QIKPDDRVQS IVKGTKQRLV 2160
INRTHASDEG PYKLMVGRVE TSCNLSVEKI KIIRGLRDLT CTETQNVVFE VELSHSGIDV 2220
VWNFKGQEIK PSSKYKIEAH GKIYKLTVLN MMKDDEGEYA FYAGENTTSG KLTVAGGAIS 2280
KPLTDQTVAE SQEAVFECEV ANPESEGEWL KDGKHLTLSN NFRSESDGHK RRLVIAAAKL 2340
DDIGEYTYKV ATSKTSAKLK VEAVKIKKTL RNLTVTETQD AIFSVELTHP DVKGVQWIKN 2400
GVVLDSNDKY EISVKGTLYS LKIKNCAMAD ESVYGFKLGR LGASARLHVE TVKIIKKPKD 2460
VTALENATVA FEVSVSHDTV PVKWFHKNVE IKPSDKHRLV SERKVHKLML QNISPSDAGE 2520
YTAVVGQLEC KAKLFVETLH ITKTMRNIEV PETKAASFEC EVSHFNVPSM WLKNGVEIEM 2580
SEKFKIVVQG KLHQLIIMNT STEDSAEYTF VCGNDQVSAT LTVTPIMITS MLKDINAEEK 2640
DTITFEVTVN YEGISYKWLK NGVEIKSTDR CQMRTKKLTH SLNIRNVHFG DAADYTFVAG 2700
KATSTATLYV EARHIEFRKH IKDIKVLEKK RAMFECEVSE PDITVQWMKD GQELQIVDRI 2760
KIQKEKYVHR LLIPSARMSD AGKYTVVAGG NMSTANLFVE GRDVRIRSIK KEVQVIEKQR 2820
AVVEFEVNED DVDAHWYKDG IEINFQVEER HQYVVERRIH RMFISEARHS DAGEYTFVAG 2880
RNRSSVTLYV NAPEPPQVLQ ELQPVTVQSG KPARFCAVIA GRPQPKISWY KEEQLLSTGF 2940
KCKFLHDGQE YTLLLIEAFP EDAAVYTCEA KNDYGVATTS ASLSVEVPEV VSPDQEMPVY 3000
PPAIVTPLQD AVTSEGRPAR FQCQVSGTDL KVSWYCRDKK IKPSRFFRMT QFEDTYQLEI 3060
AEAFPEDEGT YAFVANNAVG QVSSTATLRL EAPESILHEQ IGQQIEMEMK EELFEGEADG 3120
AGDTRGAFSD SEDIDHHSLM ARRYANRMSS TSSWPECFKP AFTQKLTFQY ALEGEPVVFT 3180
CRLVAYPTPE MTWFHNNRPV PTGFRRVIRT ENDLHQHSSS LEVQRVQARD SGSYRILAVN 3240
SEGTAESSAS LHVIQKGQDE RYLEFLKRAE QTCENTGSLG GRREERIKVG LRFTGSPFNK 3300
RQVVEQKGMM RTIHFRTASP VRRAAYVCKD EWSESKFDVR GCLSVGENFL DEETKMKLQR 3360
LREARKIFLE KRKLCLLDAS SEMNLMTMRS EDLVREAPFS REEGKIGFVH EFAEDRDRVD 3420
NSVKGIIQNP YPLPNQIHQN REPPSSVQTT GDEDLQAENS LNQETFQEES LLEGYWIEQD 3480
LAGENPQARE QLEDSVSSIV VREPSASTSN EEMCGYASSG IYEASEMSQV LTPYSSEALG 3540
TLANAEDAED IDSRGGTQRG WQEGQRHAST KAEEFKAERE EKTRSFENYI HKHPQRCPPS 3600
FLQDIESQEV YEGDSCKFVC HFQGYPQPIV TWYNNDMPIP RSQGFTTHTF ENYSTLTFPS 3660
AQPHHGGSIT CVLFNQYGTV KATSMLRVRP KPRYDSQPHK VPVWPDLADE EEELALVFDQ 3720
ARSIHPSFSQ EHPHMLKTHP SVLPSADREL LSFPVEIQIT AATPTPEQNK EYGELFELEP 3780
EATSRDQAIQ SPKHKFVFSS DITNEPPKML QEMPRSASCR EGNSVMLECL ISGEPQPAVA 3840
WFHNGVPIKQ SQKFEIEEVN YSYRLYINDV DLHDSGRYQC VAENDSGIAE SILDLTVEPI 3900
PYREYSQLEN ISGIYAQYSK NQQTQVQEES VRTHFYDNPV GPFTAQSNVK EYSVXRECFQ 3960
SLETVGQVDK IKEVYCPSPS EKLSRSMQDA SRPSDINKSH RTEFLQCQNG GHIHERSQSE 4020
GTIYPFVDEF REANIRNEVR DGFGHHGPEW GNMKVHSPSD NIHSKRTSEA VQDVEDSSVV 4080
TYDEALEGER YYPGKKVKHK IIAFEKLQRA EKGVLEKRRT KKSFVTGPQK KWGNREFALK 4140
QKQSGWSNMH QAEEVASHTE ADSSNIVMDL KQLSSQAHDE FETEEKGQQE EMLPLDQEKA 4200
ELEAPVTFDL KQFHSQIEST DMNFQDLANG QQGKRPLEPQ QPASEMANPK DIVFDLKQMY 4260
SHIDDPGEAF QGQETENRQE MCHKKEISVN QSFHDAQEEN TSILKTDHVP ESYSEVVHGE 4320
SWALFQTPSA DVKETNVSET NASVENGDKS FISQLKRAAS EEELLEDHDM GDGSTMGPAC 4380
GVTQEYEGNL ENPRGDVHGA DVPHRQLSLS QDLPFLMTGE QQDLKEQISE SIQVSGEETY 4440
QEVTVQNESF VSTMEGEKTE ESLPENLPRL EETQTTEEGA SETSLTQYLL AEGRYEVPEV 4500
RDTKRKAQLV QSESVTSMEV EEVTFNTVYE YYNQKQEFLG RPYSPESDIS IDVGSTSSED 4560
ISELDQFYSP PSSVENLESP KSLDLYFKPS GIIEPSVANS RADTLERYST PSEENGERYS 4620
TPSEGEIPER YSTPPGEALE RYSTPPGEAL ERYSTPPGEA LERYSTPPGE ALERYSTPPG 4680
EALERFFTPP GEKLERGSVP TRGPNHSRNV SMNLSKLERE DSTPNEHFHT PTDERISPYE 4740
TWRSDSFGTP NEAIEPKDNE MPPSFIEPLS KRKIYENTTL GFIIEVEGLP VPGVKWYRNR 4800
SLLEPDDRIK MERVGNVCSL EISNVQKGDG GEYMCHAVNI IGEAKSFAKV DVIPQEERAV 4860
ALPPPVTHQH VMEFDVANAN SSRTPSPQEI VLEVELGEKD VKEFEKQVKI VTVPEFTPDH 4920
KSMIVSLDIL PLNLVDPSAE SQGEEGREFK IDLEAFEMPP RFITPICDFR IPENSTAVFK 4980
CSVIGIPTPE VQWYKEYMCI EPDDTKYVIS EEKGRHSLRI RDVGPSDSAT YRCRALNSAG 5040
EAICRGFLTM GESQASAVVT RTSKVTLSSQ KEELVLRSKY ADSFFEFQVV EGPPRFIKGI 5100
SDCRAPLGTA AYFQCLVRGS PRPTVSWYKN GRVVQGSRFS AEESGIGFHN LFITGLTKGD 5160
EGEYSCVATN NSGTARSNAI LTLL 5184 
Gene Ontology
  
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2.
 IPR015129; Titin_Z. 
Pfam
 PF07679; I-set
 PF09042; Titin_Z 
SMART
 SM00409; IG
 SM00408; IGc2 
PROSITE
 PS50835; IG_LIKE 
PRINTS