CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011300
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytosolic iron-sulfur protein assembly protein 1 
Protein Synonyms/Alias
  
Gene Name
 CIA1 
Gene Synonyms/Alias
 YDR267C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
302VYEINVVKWLELNGKubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. 
Sequence Annotation
 REPEAT 12 53 WD 1.
 REPEAT 56 95 WD 2.
 REPEAT 105 144 WD 3.
 REPEAT 151 190 WD 4.
 REPEAT 195 236 WD 5.
 REPEAT 248 286 WD 6.
 REPEAT 292 330 WD 7.  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Nucleus; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 330 AA 
Protein Sequence
MASINLIKSL KLYKEKIWSF DFSQGILATG STDRKIKLVS VKYDDFTLID VLDETAHKKA 60
IRSVAWRPHT SLLAAGSFDS TVSIWAKEES ADRTFEMDLL AIIEGHENEV KGVAWSNDGY 120
YLATCSRDKS VWIWETDESG EEYECISVLQ EHSQDVKHVI WHPSEALLAS SSYDDTVRIW 180
KDYDDDWECV AVLNGHEGTV WSSDFDKTEG VFRLCSGSDD STVRVWKYMG DDEDDQQEWV 240
CEAILPDVHK RQVYNVAWGF NGLIASVGAD GVLAVYEEVD GEWKVFAKRA LCHGVYEINV 300
VKWLELNGKT ILATGGDDGI VNFWSLEKAA 330 
Gene Ontology
 GO:0005829; C:cytosol; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0016226; P:iron-sulfur cluster assembly; IMP:SGD.
 GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD.
 GO:0002098; P:tRNA wobble uridine modification; IMP:SGD. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.