CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018400
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Xylose isomerase 
Protein Synonyms/Alias
  
Gene Name
 xylA 
Gene Synonyms/Alias
 STM3661 
Created Date
 July 27, 2013 
Organism
 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 
NCBI Taxa ID
 99287 
Lysine Modification
Position
Peptide
Type
References
381VEDGELDKRVAKRYAacetylation[1]
385ELDKRVAKRYAGWNGacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786
Functional Description
  
Sequence Annotation
 ACT_SITE 101 101 By similarity.
 ACT_SITE 104 104 By similarity.
 METAL 232 232 Magnesium 1 (By similarity).
 METAL 268 268 Magnesium 1 (By similarity).
 METAL 268 268 Magnesium 2 (By similarity).
 METAL 271 271 Magnesium 2 (By similarity).
 METAL 296 296 Magnesium 1 (By similarity).
 METAL 307 307 Magnesium 2 (By similarity).
 METAL 309 309 Magnesium 2 (By similarity).
 METAL 339 339 Magnesium 1 (By similarity).  
Keyword
 Carbohydrate metabolism; Complete proteome; Cytoplasm; Isomerase; Magnesium; Metal-binding; Pentose shunt; Reference proteome; Xylose metabolism. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 440 AA 
Protein Sequence
MQAYFDQLDR VRYEGPQSTN PLAFRHYNPD ELVLGKRMED HLRFAACYWH TFCWNGADMF 60
GVGAFNRPWQ QPGEALELAK RKADVAFEFF HKLNVPFYCF HDVDVSPEGA SLKEYKNNFA 120
QMVDVLAAKQ EQSGVKLLWG TANCFTNPRY GAGAATNPDP EVFSWAATQV VTAMNATHKL 180
GGENYVLWGG REGYETLLNT DLRQEREQIG RFMQMVVEHK HKMGFQGTLL IEPKPQEPTK 240
HQYDYDVATV YGFLKQFGLE KEIKVNIEAN HATLAGHSFH HEIATAIALG IFGSVDANRG 300
DAQLGWDTDQ FPISVEENAL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY DLFYGHIGAM 360
DTMALSLKIA ARMVEDGELD KRVAKRYAGW NGELGQQILK GQLSLGELAQ YAEQHNLAPV 420
HQSGHQELLE NLVNRYLFDK 440 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0009045; F:xylose isomerase activity; IEA:HAMAP.
 GO:0042732; P:D-xylose metabolic process; IEA:HAMAP.
 GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP. 
Interpro
 IPR013022; Xyl_isomerase-like_TIM-brl.
 IPR013452; Xylose_isom_bac.
 IPR001998; Xylose_isomerase. 
Pfam
 PF01261; AP_endonuc_2 
SMART
  
PROSITE
 PS51415; XYLOSE_ISOMERASE 
PRINTS
 PR00688; XYLOSISMRASE.