CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013097
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Proton myo-inositol cotransporter 
Protein Synonyms/Alias
 H(+)-myo-inositol cotransporter; Hmit; H(+)-myo-inositol symporter 
Gene Name
 Slc2a13 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
590LPETKGKKLEEIESLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 H(+)-myo-inositol cotransporter. Can also transport related stereoisomers (By similarity). 
Sequence Annotation
 MOD_RES 629 629 Phosphoserine (By similarity).
 MOD_RES 634 634 Phosphoserine (By similarity).
 CARBOHYD 422 422 N-linked (GlcNAc...) (Potential).
 CARBOHYD 447 447 N-linked (GlcNAc...) (Potential).
 CARBOHYD 474 474 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 637 AA 
Protein Sequence
MSRKASEDVE YTLRSLSSLM GERRRRQPEP GAPGGERSLL AAESAASLQG AELERAARRQ 60
FQRDETPAFV YAAAAFSALG GFLFGYDTGV VSGAMLLLRR QMRLGAMWQE LLVSGAVGAA 120
AVAALAGGAL NGALGRRSAI LLASALCTVG SAVLAAAANK ETLLAGRLVV GLGIGIASMT 180
VPVYIAEVSP PNLRGRLVTI NTLFITGGQF FASVVDGAFS YLQKDGWRYM LGLAAIPAVI 240
QFLGFLFLPE SPRWLIQKGQ TQKARRILSQ MRGNQTIDEE YDSIRNSIEE EEKEATAAGP 300
IICRMLSYPP TRRALVVGCG LQMFQQLSGI NTIMYYSATI LQMSGVEDDR LAIWLASITA 360
FTNFIFTLVG VWLVEKVGRR KLTFGSLAGT TVALIILALG FLLSAQVSPR VTFRPTTPSD 420
QNTTCTGYSY CNECMLDPDC GFCYKINGSA VIDSSCVPVN KASTTEAAWG RCDNETKFKA 480
EGAHWAYSFC PTPYSWTALV GLVLYLVFFA PGMGPMPWTV NSEIYPLWAR STGNACSAGI 540
NWIFNVLVSL TFLHTAEYLT YYGAFFLYAG FAAVGLLFVY GCLPETKGKK LEEIESLFDH 600
RLCSCGAADS DEGRYIEYIR VKGSNYHLSD NDASDVE 637 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0022891; F:substrate-specific transmembrane transporter activity; IEA:InterPro. 
Interpro
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF00083; Sugar_tr 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 
PRINTS
 PR00171; SUGRTRNSPORT.