| Tag | Content |
|---|
| CPLM ID | CPLM-019912 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dehydrodolichyl diphosphate synthase |
Protein Synonyms/Alias | Dedol-PP synthase; Cis-isoprenyltransferase; CIT; Cis-IPTase |
Gene Name | Dhdds |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 87 | IENFKRSKSEVDGLL | ubiquitination | [1] | | 316 | ERVQGFLKALELKRA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein. |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 333 AA |
Protein Sequence | MSWIKEGELS LWERFCANII KAGPVPKHIA FIMDGNRRYA KKCQVERQEG HTQGFNKLAE 60
TLRWCLNLGI LEVTVYAFSI ENFKRSKSEV DGLLDLARQK FSCLMEEQEK LQKHGVCIRV 120
LGDLHLLPLD LQEKIAHAIQ ATKNYNKCFL NVCFAYTSRH EIANAVREMA WGVEQGLLEP 180
SDVSESLLDK CLYSNHSPHP DILIRTSGEV RLSDFLLWQT SHSCLVFQPV LWPEYTFWNL 240
CEAILQFQRN HGALQQKARD MYAEERKRRQ LERDQAAVTE QLLREGLQAS GDAQLRRTRL 300
HKLSTKREER VQGFLKALEL KRANWLALWG TASA 334 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro. GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |