CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013706
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP synthase subunit alpha 
Protein Synonyms/Alias
 ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha 
Gene Name
 atpA 
Gene Synonyms/Alias
 GK3360 
Created Date
 July 27, 2013 
Organism
 Geobacillus kaustophilus (strain HTA426) 
NCBI Taxa ID
 235909 
Lysine Modification
Position
Peptide
Type
References
458EDVRRFEKEFYLWLDacetylation[1]
Reference
 [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus.
 Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG.
 Proteomics. 2013 Aug;13(15):2278-82. [PMID: 23696451] 
Functional Description
 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity). 
Sequence Annotation
 NP_BIND 169 176 ATP (By similarity).  
Keyword
 ATP synthesis; ATP-binding; Cell membrane; CF(1); Complete proteome; Hydrogen ion transport; Hydrolase; Ion transport; Membrane; Nucleotide-binding; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 502 AA 
Protein Sequence
MSIRAEEISA LIKQQIENYE SQIQVSDVGT VIQVGDGIAR AHGLDNVMSG ELVEFANGVM 60
GMALNLEENN VGIVILGPYT GIKEGDEVRR TGRIMEVPVG EALIGRVVNP LGQPVDGLGP 120
VETTETRPIE SPAPGVMDRR SVHEPLQTGI KAIDALVPIG RGQRELIIGD RQTGKTSVAI 180
DTIINQKDQN MICIYVAIGQ KESTVRTVVE TLRKHGALDY TIVVTASASQ PAPLLFLAPY 240
AGVAMGEYFM YKGQHVLVVY DDLSKQAAAY RELSLLLRRP PGREAYPGDI FYLHSRLLER 300
AAKLSDAKGG GSLTALPFVE TQAGDISAYI PTNVISITDG QIFLQSDLFF SGVRPAINAG 360
LSVSRVGGAA QIKAMKKVAG TLRLDLAAYR ELEAFAQFGS DLDKATQAKL ARGARTVEVL 420
KQDLHQPIPV EKQVLIIYAL TRGFLDDIPV EDVRRFEKEF YLWLDQNGQH LLEHIRTTKD 480
LPNEDDLNKA IEAFKKTFVV SQ 502 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0045261; C:proton-transporting ATP synthase complex, catalytic core F(1); IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:HAMAP.
 GO:0046933; F:proton-transporting ATP synthase activity, rotational mechanism; IEA:HAMAP.
 GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
 GO:0042777; P:plasma membrane ATP synthesis coupled proton transport; IEA:HAMAP. 
Interpro
 IPR020003; ATPase_a/bsu_AS.
 IPR004100; ATPase_a/bsu_N.
 IPR005294; ATPase_F1-cplx_asu.
 IPR023366; ATPase_F1/A1-cplx_a_su_N.
 IPR000793; ATPase_F1/V1/A1-cplx_a/bsu_C.
 IPR000194; ATPase_F1/V1/A1_a/bsu_nucl-bd.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00006; ATP-synt_ab
 PF00306; ATP-synt_ab_C
 PF02874; ATP-synt_ab_N 
SMART
  
PROSITE
 PS00152; ATPASE_ALPHA_BETA 
PRINTS