CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031684
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Basic leucine zipper and W2 domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 BZW2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
41NYAQVFNKLIRRYKYubiquitination[1, 2, 3]
59AFEDEMKKLLLFLKAubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 343 AA 
Protein Sequence
MLAPGGTRID DGDKTKMTNH CVFSANEDHE TIRNYAQVFN KLIRRYKYLE KAFEDEMKKL 60
LLFLKAFSET EQTKLAMLSG ILLGNGTLPA TILTSLFTDS LVKEGIAASF AVKLFKAWMA 120
EKDANSVTSS LRKANLDKRL LELFPVNRQS VDHFAKYFTD AGLKELSDFL RVQQSLGTRK 180
ELQKELQERL SQECPIKEVV LYVKEEMKRN DLPETAVIGL LWTCIMNAVE WNKKEELVAE 240
QALKHLKQYA PLLAVFSSQG QSELILLQKV QEYCYDNIHF MKAFQKIVVL FYKADVLSEE 300
AILKWYKEAH VAKGKSVFLD QMKKFVEWLQ NAEEESESEG EEN 343 
Gene Ontology
 GO:0016070; P:RNA metabolic process; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR016021; MIF4-like_typ_1/2/3.
 IPR003307; W2_domain. 
Pfam
 PF02020; W2 
SMART
 SM00515; eIF5C 
PROSITE
 PS51363; W2 
PRINTS