UniProt Accession

 H0YME6_HUMAN; H0YME6 

Genbank Protein ID

 AC027237 

Genbank Nucleotide ID

  

Protein Name

 Kinesin-like protein KIF23 

Protein Synonyms/Alias

  

Gene Name

 KIF23 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
7	*MKSARAKTPRKPTV	ubiquitination	[1]
11	ARAKTPRKPTVKKGS	ubiquitination	[1]
23	KGSQTNLKDPVGVYC	ubiquitination	[2]
149	SIGSFQAKRYVFKSN	ubiquitination	[3]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 371 AA 

Protein Sequence

Gene Ontology

 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 

Interpro

 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00225; Kinesin 

SMART

 SM00129; KISc 

PROSITE

 PS50067; KINESIN_MOTOR_DOMAIN2 

PRINTS

 PR00380; KINESINHEAVY.